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IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1, IMPA1)

Short Description: This gene encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Nov 2009].
More information related to gene IMPA1.

Products related to IMPA1 Gene:

66 results :

Human IMPA1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5745065
Datasheet
Catalog No. ABIN5745065
Type:
ORF
Application:
Cloning
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
Species:
Human
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Insert length:
834 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human IMPA1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5745066
Datasheet
Catalog No. ABIN5745066
Type:
ORF
Application:
Cloning
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
Species:
Human
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Insert length:
834 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human IMPA1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4476975
Datasheet
Catalog No. ABIN4476975
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
Species:
Human
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Insert length:
834 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human IMPA1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4476974
Datasheet
Catalog No. ABIN4476974
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
Species:
Human
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Insert length:
834 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat IMPA1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_032057
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242745
Datasheet
Catalog No. ABIN5242745
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_032057
Species:
Rat
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Impa1
Format:
Viral Particles
Storage:
-80 °C
Mouse IMPA1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_018864
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242743
Datasheet
Catalog No. ABIN5242743
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_018864
Species:
Mouse
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Impa1
Format:
Viral Particles
Storage:
-80 °C
Human IMPA1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_005536
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5242741
Datasheet
Catalog No. ABIN5242741
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_005536
Species:
Human
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of IMPA1
Format:
Viral Particles
Storage:
-80 °C
Rat IMPA1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_032057
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127320
Datasheet
Catalog No. ABIN5127320
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_032057
Species:
Rat
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Impa1
Format:
Viral Particles
Storage:
-80 °C
Mouse IMPA1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_018864
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127318
Datasheet
Catalog No. ABIN5127318
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_018864
Species:
Mouse
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Impa1
Format:
Viral Particles
Storage:
-80 °C
Human IMPA1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_005536
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5127316
Datasheet
Catalog No. ABIN5127316
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1)
NCBI Accession:
NM_005536
Species:
Human
Synonyms:
impa1, Impa1, IMPA1, impa1.S
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of IMPA1
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pDONR223
    • pCMV6-XL5
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Spectinomycin
    • Chloramphenicol
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to IMPA1

  • inositol monophosphatase 1 (impa1)
  • inositol(myo)-1(or 4)-monophosphatase 1 (impa1)
  • inositol (myo)-1(or 4)-monophosphatase 1 (Impa1)
  • inositol monophosphatase 1 (Impa1)
  • inositol monophosphatase (impa1)
  • inositol monophosphatase 1 (IMPA1)
  • inositol(myo)-1(or 4)-monophosphatase 1 S homeolog (impa1.S)
  • inositol(myo)-1(or 4)-monophosphatase 1 (IMPA1)
  • 2610002K09Rik
  • 2900059K10Rik
  • AI325909
  • IMP
  • IMPA
  • impa
  • zgc:100926

Gene-IDs for different species

Protein level used designations for IMPA1

  • inositol monophosphatase 1
  • Inositol monophosphatase
  • IMP 1
  • IMPase 1
  • inositol-1(or 4)-monophosphatase 1
  • lithium-sensitive myo-inositol monophosphatase A1
  • myo-inositol monophosphatase
Other products related to IMPA1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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