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ITPK1 (Inositol-Tetrakisphosphate 1-Kinase, ITPK1)

Short Description: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.
More information related to gene ITPK1.

Products related to ITPK1 Gene:

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66 results

Human ITPK1 shRNA in Retroviral Vector (GFP tag)
OriGene tg312068 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3736913
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse ITPK1 shRNA in Retroviral Vector (GFP tag)
OriGene tg514685 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3696681
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse ITPK1 shRNA in Retroviral Vector (RFP tag)
OriGene tf514685 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3676982
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human ITPK1 shRNA in Lentiviral Vector (GFP tag)
OriGene tl312068 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3757251
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human ITPK1 shRNA in Retroviral Vector
OriGene tr312068 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3654011
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse ITPK1 shRNA in Retroviral Vector
OriGene tr514685 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3547687
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse ITPK1 siRNA Oligo
OriGene sr413888 RNAi ITPK1 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Inositol-Tetrakisphosphate 1-Kinase
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3269962
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human ITPK1 cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene sc325066 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_001142593,NP_001136065
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3301747
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human ITPK1 cDNA Clone in Mammalian Expression Vector
OriGene sc323759 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
NCBI Accession:
NM_014216,NP_055031
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3316911
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Mouse ITPK1 shRNA in Lentiviral Vector (GFP tag)
OriGene tl514685 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3527279
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pCas-Guide
    • pDONR223
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC
    • pCMV6-XL4
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to ITPK1

  • inositol-tetrakisphosphate 1-kinase (ITPK1)
  • inositol 1,3,4-triphosphate 5/6 kinase (Itpk1)
  • inositol-tetrakisphosphate 1-kinase L homeolog (itpk1.L)
  • inositol-tetrakisphosphate 1-kinase a (itpk1a)
  • inositol-tetrakisphosphate 1-kinase (Itpk1)
  • BC031182
  • ITRPK1
  • wu:fj15d08
  • zgc:56075

Gene-IDs for different species

Protein level used designations for ITPK1

  • inositol 1,3,4-triphosphate 5/6 kinase
  • inositol 1,3,4-trisphosphate 5/6 kinase
  • inositol 1,3,4-trisphosphate 5/6-kinase
  • inositol-triphosphate 5/6-kinase
  • ins(1,3,4)P(3) 5/6-kinase
  • inositol-tetrakisphosphate 1-kinase
Other products related to ITPK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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