ITPK1 (Inositol-Tetrakisphosphate 1-Kinase, ITPK1)
Short Description: Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.
More information related to gene ITPK1.
More information related to gene ITPK1.
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66 results
OriGene rc204537l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
- NCBI Accession:
- NM_014216,NP_055031
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5436225
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc227205
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
- NCBI Accession:
- NM_001142593,NP_001136065
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5436222
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc227538
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
- NCBI Accession:
- NM_001142594,NP_001136066
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5436223
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc204537
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
- NCBI Accession:
- NM_014216,NP_055031
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5436221
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc204537l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Inositol-Tetrakisphosphate 1-Kinase (ITPK1)
- NCBI Accession:
- NM_014216,NP_055031
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5436228
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr302486
RNAi
ITPK1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Inositol-Tetrakisphosphate 1-Kinase
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342268
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to ITPK1
- inositol-tetrakisphosphate 1-kinase (ITPK1)
- inositol 1,3,4-triphosphate 5/6 kinase (Itpk1)
- inositol-tetrakisphosphate 1-kinase L homeolog (itpk1.L)
- inositol-tetrakisphosphate 1-kinase a (itpk1a)
- inositol-tetrakisphosphate 1-kinase (Itpk1)
- BC031182
- ITRPK1
- wu:fj15d08
- zgc:56075
Gene-IDs for different species
Protein level used designations for ITPK1
- inositol 1,3,4-triphosphate 5/6 kinase
- inositol 1,3,4-trisphosphate 5/6 kinase
- inositol 1,3,4-trisphosphate 5/6-kinase
- inositol-triphosphate 5/6-kinase
- ins(1,3,4)P(3) 5/6-kinase
- inositol-tetrakisphosphate 1-kinase
Proteomics products related to ITPK1 Gene
Other products related to ITPK1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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