Laminin gamma 1 (Laminin, gamma 1, LAMC1)
Short Description: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis. [provided by RefSeq, Aug 2011].
More information related to gene Laminin gamma 1.
More information related to gene Laminin gamma 1.
Products related to Laminin gamma 1 Gene:
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48 results
OriGene kn416928
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Laminin, gamma 1 (LAMC1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3240804
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn217665
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Laminin, gamma 1 (LAMC1)
- NCBI Accession:
- NM_053966,NP_446418
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3327889
$1,497.87
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene sc118737
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL4
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Laminin, gamma 1 (LAMC1)
- NCBI Accession:
- NM_002293,NP_002284
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL4
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3378642
$1,363.23
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene mc224746
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Laminin, gamma 1 (LAMC1)
- NCBI Accession:
- NM_010683,NP_034813
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3375533
$1,497.87
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 6 to 9 Business Days
OriGene rc216928
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Laminin, gamma 1 (LAMC1)
- NCBI Accession:
- NM_002293,NP_002284
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5354552
$1,362.24
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr217665
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Laminin, gamma 1 (LAMC1)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5354553
$1,496.88
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 36 to 37 Business Days
OriGene rg216928
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Laminin, gamma 1 (LAMC1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5354551
$781.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr302649
RNAi
LAMC1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Laminin, gamma 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3342431
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
Synonyms and alternative names related to Laminin gamma 1
- putative laminin gamma-1 chain (Smp_163810)
- laminin subunit gamma 1 (lamc1)
- laminin, gamma 1 (Lamc1)
- laminin subunit gamma 1 (Lamc1)
- laminin, gamma 1 (lamc1)
- laminin subunit gamma 1 (LAMC1)
- B2e
- lamb2
- Lamb2
- LAMB2
- sly
Gene-IDs for different species
Protein level used designations for Laminin gamma 1
- laminin gamma-1 chain
- laminin subunit gamma-1
- S-LAM gamma
- S-laminin subunit gamma
- laminin B2 chain
- laminin-1 subunit gamma
- laminin-10 subunit gamma
- laminin-11 subunit gamma
- laminin-2 subunit gamma
- laminin-3 subunit gamma
- laminin-4 subunit gamma
- laminin-6 subunit gamma
- laminin-7 subunit gamma
- laminin-8 subunit gamma
- laminin-9 subunit gamma
- shortstop
- shp
- sleepy
Proteomics products related to Laminin gamma 1 Gene
Other products related to Laminin gamma 1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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