LRP2 (Low Density Lipoprotein Receptor-Related Protein 2, LRP2)
Short Description: The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling\; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009].
More information related to gene LRP2.
More information related to gene LRP2.
Products related to LRP2 Gene:
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45 results
OriGene kn213707
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3241536
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn213120
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
- NCBI Accession:
- NM_030827,NP_110454
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3307231
$4,036.23
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 71 to 72 Business Days
OriGene rg213707
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5404585
$5,694.48
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc213707
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
- NCBI Accession:
- NM_004525,NP_004516
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5404586
$5,496.48
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
OriGene rr213120
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5404587
$4,035.24
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 71 to 72 Business Days
Synonyms and alternative names related to LRP2
- LDL receptor related protein 2 (LRP2)
- low density lipoprotein receptor-related protein 2a (lrp2a)
- low density lipoprotein receptor-related protein 2 (LRP2)
- low-density lipoprotein receptor-related protein 2 (LRP2.3)
- LDL receptor related protein 2 L homeolog (lrp2.L)
- low-density lipoprotein receptor-related protein 2 (LOC100183506)
- LDL receptor related protein 2 (lrp2)
- low density lipoprotein receptor-related protein 2 (Lrp2)
- LDL receptor related protein 2 (Lrp2)
- AI315343
- AW536255
- D230004K18Rik
- dbs
- DBS
- gp330
- GP330
- Gp330
- im:680590
- lrp2
- megalin
- Megalin
Gene-IDs for different species
Protein level used designations for LRP2
- low density lipoprotein-related protein 2
- gp330b
- low-density lipoprotein receptor-related protein 2
- megalin
- low density lipoprotein receptor-related protein 2
- low-density lipoprotein receptor-related protein 2-like
- Heymann nephritis antigen homolog
- LRP-2
- calcium sensor protein
- glycoprotein 330
- gp330
Proteomics products related to LRP2 Gene
Other products related to LRP2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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