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LRP2 (Low Density Lipoprotein Receptor-Related Protein 2, LRP2)

Short Description: The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling\; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009].
More information related to gene LRP2.

Products related to LRP2 Gene:

45 results :

Rat LRP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_030827
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235824
Datasheet
Catalog No. ABIN5235824
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_030827
Species:
Rat
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Lrp2
Format:
Viral Particles
Storage:
-80 °C
Mouse LRP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_001081088
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235822
Datasheet
Catalog No. ABIN5235822
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_001081088
Species:
Mouse
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Lrp2
Format:
Viral Particles
Storage:
-80 °C
Human LRP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_004525
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235820
Datasheet
Catalog No. ABIN5235820
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_004525
Species:
Human
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of LRP2
Format:
Viral Particles
Storage:
-80 °C
Mouse LRP2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_001081088
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120458
Datasheet
Catalog No. ABIN5120458
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_001081088
Species:
Mouse
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Lrp2
Format:
Viral Particles
Storage:
-80 °C
Rat LRP2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_030827
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120460
Datasheet
Catalog No. ABIN5120460
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_030827
Species:
Rat
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Lrp2
Format:
Viral Particles
Storage:
-80 °C
Human LRP2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_004525
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120456
Datasheet
Catalog No. ABIN5120456
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_004525
Species:
Human
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of LRP2
Format:
Viral Particles
Storage:
-80 °C
Rat LRP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_030827
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235823
Datasheet
Catalog No. ABIN5235823
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_030827
Species:
Rat
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Lrp2
Format:
Viral Particles
Storage:
-80 °C
Mouse LRP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_001081088
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235821
Datasheet
Catalog No. ABIN5235821
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_001081088
Species:
Mouse
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of Lrp2
Format:
Viral Particles
Storage:
-80 °C
Human LRP2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_004525
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5235819
Datasheet
Catalog No. ABIN5235819
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_004525
Species:
Human
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of LRP2
Format:
Viral Particles
Storage:
-80 °C
Human LRP2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_004525
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5120455
Datasheet
Catalog No. ABIN5120455
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Low Density Lipoprotein Receptor-Related Protein 2 (LRP2)
NCBI Accession:
NM_004525
Species:
Human
Synonyms:
LRP2, lrp2a, LRP2.3, lrp2.L, LOC100183506, lrp2, Lrp2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with a set of 3 gRNAs (3 x 300 μL) covering different sequences of LRP2
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • HA tag
    • His-GST
    • His-MBP
    • Myc-DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • gRNA + Cas9
    • shRNA
    • ORF
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Liquid
    • Lyophilized
    • Viral Particles

Synonyms and alternative names related to LRP2

  • LDL receptor related protein 2 (LRP2)
  • low density lipoprotein receptor-related protein 2a (lrp2a)
  • low density lipoprotein receptor-related protein 2 (LRP2)
  • low-density lipoprotein receptor-related protein 2 (LRP2.3)
  • LDL receptor related protein 2 L homeolog (lrp2.L)
  • low-density lipoprotein receptor-related protein 2 (LOC100183506)
  • LDL receptor related protein 2 (lrp2)
  • low density lipoprotein receptor-related protein 2 (Lrp2)
  • LDL receptor related protein 2 (Lrp2)
  • AI315343
  • AW536255
  • D230004K18Rik
  • dbs
  • DBS
  • gp330
  • GP330
  • Gp330
  • im:680590
  • lrp2
  • megalin
  • Megalin

Gene-IDs for different species

Protein level used designations for LRP2

  • low density lipoprotein-related protein 2
  • gp330b
  • low-density lipoprotein receptor-related protein 2
  • megalin
  • low density lipoprotein receptor-related protein 2
  • low-density lipoprotein receptor-related protein 2-like
  • Heymann nephritis antigen homolog
  • LRP-2
  • calcium sensor protein
  • glycoprotein 330
  • gp330
Other products related to LRP2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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