Metabotropic Glutamate Receptor 1 (Glutamate Receptor, Metabotropic 1, GRM1)
Short Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms\; some of which may have distinct functions. [provided by RefSeq, Jul 2008].
More information related to gene Metabotropic Glutamate Receptor 1.
More information related to gene Metabotropic Glutamate Receptor 1.
Products related to Metabotropic Glutamate Receptor 1 Gene:
Recommended next Filters:
86 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_000838
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_000838
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_001114330
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_001114329
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_001114333
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_016976
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_001114333
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_017011
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- NCBI Accession:
- NM_001114330
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Glutamate Receptor, Metabotropic 1 (GRM1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
Synonyms and alternative names related to Metabotropic Glutamate Receptor 1
- glutamate metabotropic receptor 1 (GRM1)
- glutamate receptor, metabotropic 1a (grm1a)
- metabotropic glutamate receptor 1 (mGlutR1)
- glutamate receptor, metabotropic 1 (Grm1)
- glutamate receptor, metabotropic 1 (GRM1)
- 4930455H15Rik
- ENSMUSG00000075319
- fj39d05
- GB18621
- Glura
- Gm10828
- GPRC1A
- Gprc1a
- MGLU1
- MGLUR1
- mGluR1
- mGlutR
- nmf373
- rcw
- SCAR13
- si:ch211-51a19.1
- wobl
- wu:fj39d05
Gene-IDs for different species
Protein level used designations for Metabotropic Glutamate Receptor 1
- metabotropic glutamate receptor 1
- metabotropic glutamate receptor A
- G protein coupled receptor, family C, group 1, member A
- G protein-coupled receptor, family C, group 1, member A
- G protein coupled receptor family C group 1 member A
- mGluR1
Proteomics products related to Metabotropic Glutamate Receptor 1 Gene
Other products related to Metabotropic Glutamate Receptor 1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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