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MLH1 (MutL Homolog 1, MLH1)

Short Description: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009].
More information related to gene MLH1.

Products related to MLH1 Gene:

75 results :

Human MLH1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5726293
Datasheet
Catalog No. ABIN5726293
Type:
ORF
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Insert length:
2271 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human MLH1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4478111
Datasheet
Catalog No. ABIN4478111
Type:
cDNA
Application:
Protein Expression
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Insert length:
2271 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat MLH1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
NCBI Accession:
NM_031053
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5092496
Datasheet
Catalog No. ABIN5092496
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
NCBI Accession:
NM_031053
Species:
Rat
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mlh1
Format:
Viral Particles
Storage:
-80 °C
Mouse MLH1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
NCBI Accession:
NM_026810
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5092494
Datasheet
Catalog No. ABIN5092494
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
NCBI Accession:
NM_026810
Species:
Mouse
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Mlh1
Format:
Viral Particles
Storage:
-80 °C
Human MLH1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
NCBI Accession:
NM_000249
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5092492
Datasheet
Catalog No. ABIN5092492
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
NCBI Accession:
NM_000249
Species:
Human
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of MLH1
Format:
Viral Particles
Storage:
-80 °C
Human MLH1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4835342
Datasheet
Catalog No. ABIN4835342
Type:
cDNA
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Insert length:
2271 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MLH1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4621582
Datasheet
Catalog No. ABIN4621582
Type:
cDNA
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Insert length:
2271 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MLH1 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4706212
Datasheet
Catalog No. ABIN4706212
Type:
cDNA
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Insert length:
2271 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human MLH1 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4439206
Datasheet
Catalog No. ABIN4439206
Type:
cDNA
Application:
Protein Expression
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
Species:
Human
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Insert length:
2271 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse MLH1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
NCBI Accession:
NM_026810
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5726294
Datasheet
Catalog No. ABIN5726294
Type:
ORF
Application:
Cloning
Gene:
MutL Homolog 1, Colon Cancer, Nonpolyposis Type 2 (E. Coli) (MLH1)
NCBI Accession:
NM_026810
Species:
Mouse
Synonyms:
MLH1, Mlh1, mlh1.S, mlh1, LOC588545
Insert length:
2283 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-XL5
    • pcDNA3.1+C-(K)-DYK
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to MLH1

  • mutL homolog 1 (MLH1)
  • CG11482 gene product from transcript CG11482-RB (Mlh1)
  • mutL homolog 1 S homeolog (mlh1.S)
  • mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (mlh1)
  • DNA mismatch repair protein Mlh1 (LOC588545)
  • mutL homolog 1 (mlh1)
  • mutL homolog 1 (Mlh1)
  • 1110035C23Rik
  • AI317206
  • AI325952
  • AI561766
  • CG11482
  • COCA2
  • Dmel\\CG11482
  • dmlh-1
  • dmlh1
  • FCC2
  • hMLH1
  • HNPCC
  • HNPCC2
  • LOC100232198
  • MLH1
  • zgc:66301

Gene-IDs for different species

Protein level used designations for MLH1

  • MutL protein homolog 1
  • CG11482-PA
  • CG11482-PB
  • Mlh1-PA
  • Mlh1-PB
  • DNA mismatch repair protein Mlh1
  • mutL-like protein 1
  • mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
  • DNA mismatch repair protein Mlh1-like
  • colon cancer, nonpolyposis type 2
  • mutL protein homolog 1
  • mismatch repair protein 1
Other products related to MLH1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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