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NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3, NR1I3)

Short Description: This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene NR1I3.

Products related to NR1I3 Gene:

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183 results

Human NR1I3 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739566
Catalog No. ABIN5739566
Type:
ORF
Application:
Cloning
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Synonyms:
NR1I3, Nr1i3
Insert length:
1059 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human NR1I3 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4478790
Catalog No. ABIN4478790
Type:
cDNA
Application:
Protein Expression
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Synonyms:
NR1I3, Nr1i3
Insert length:
1059 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human NR1I3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_001077472
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117066
Catalog No. ABIN5117066
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_001077472
Species:
Human
Synonyms:
NR1I3, Nr1i3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of NR1I3
Format:
Viral Particles
Storage:
-80 °C
Mouse NR1I3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_009799
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117068
Catalog No. ABIN5117068
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_009799
Species:
Mouse
Synonyms:
NR1I3, Nr1i3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Car1
Format:
Viral Particles
Storage:
-80 °C
Rat NR1I3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_022941
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117074
Catalog No. ABIN5117074
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_022941
Species:
Rat
Synonyms:
NR1I3, Nr1i3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nr1i3
Format:
Viral Particles
Storage:
-80 °C
Rat NR1I3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_001107660
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117072
Catalog No. ABIN5117072
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_001107660
Species:
Rat
Synonyms:
NR1I3, Nr1i3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Car1
Format:
Viral Particles
Storage:
-80 °C
Mouse NR1I3 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_009803
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117070
Catalog No. ABIN5117070
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
NCBI Accession:
NM_009803
Species:
Mouse
Synonyms:
NR1I3, Nr1i3
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nr1i3
Format:
Viral Particles
Storage:
-80 °C
Human NR1I3 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4836352
Catalog No. ABIN4836352
Type:
cDNA
Application:
Cloning
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Synonyms:
NR1I3, Nr1i3
Insert length:
1059 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human NR1I3 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4707222
Catalog No. ABIN4707222
Type:
cDNA
Application:
Cloning
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Synonyms:
NR1I3, Nr1i3
Insert length:
1059 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human NR1I3 cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4439885
Catalog No. ABIN4439885
Type:
cDNA
Application:
Protein Expression
Gene:
Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3)
Species:
Human
Synonyms:
NR1I3, Nr1i3
Insert length:
1059 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pcDNA3.1+C-(K)-DYK
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-XL5
    • pCMV6-Neo
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to NR1I3

  • nuclear receptor subfamily 1 group I member 3 (NR1I3)
  • nuclear receptor subfamily 1, group I, member 3 (Nr1i3)
  • AA209988
  • AI551208
  • CAR
  • CAR-beta
  • CAR1
  • Care2
  • CXR
  • ESTM32
  • MB67

Gene-IDs for different species

Protein level used designations for NR1I3

  • constitutive androstane receptor
  • constitutively transactivates RAREs
  • nuclear receptor subfamily 1 group I member 3
  • orphan nuclear receptor MB67
  • constitutive androstane receptor NR1I3
  • nuclear receptor constitutive active receptor
  • strain Fischer nuclear receptor (CAR)
  • constitutive activator of retinoid response
  • constitutive active receptor
  • constitutive active response
  • constitutive androstane nuclear receptor variant 2
  • constitutive androstane nuclear receptor variant 3
  • constitutive androstane nuclear receptor variant 4
  • constitutive androstane nuclear receptor variant 5
  • orphan nuclear hormone receptor
  • xenobiotic receptor
Other products related to NR1I3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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