Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@genomics-online.com

NSMCE2 (E3 SUMO-Protein Ligase NSE2, NSMCE2)

Short Description: E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
More information related to gene NSMCE2.

Products related to NSMCE2 Gene:

64 results :

Human NSMCE2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5761242
Datasheet
Catalog No. ABIN5761242
Type:
ORF
Application:
Cloning
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
Species:
Human
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Insert length:
744 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human NSMCE2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4478823
Datasheet
Catalog No. ABIN4478823
Type:
cDNA
Application:
Protein Expression
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
Species:
Human
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Insert length:
744 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat NSMCE2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_001024876
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5274565
Datasheet
Catalog No. ABIN5274565
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_001024876
Species:
Rat
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nsmce2
Format:
Viral Particles
Storage:
-80 °C
Mouse NSMCE2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_026746
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5274563
Datasheet
Catalog No. ABIN5274563
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_026746
Species:
Mouse
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nsmce2
Format:
Viral Particles
Storage:
-80 °C
Human NSMCE2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_173685
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5274561
Datasheet
Catalog No. ABIN5274561
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_173685
Species:
Human
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of NSMCE2
Format:
Viral Particles
Storage:
-80 °C
Rat NSMCE2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_001024876
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5158985
Datasheet
Catalog No. ABIN5158985
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_001024876
Species:
Rat
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nsmce2
Format:
Viral Particles
Storage:
-80 °C
Mouse NSMCE2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_026746
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5158983
Datasheet
Catalog No. ABIN5158983
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_026746
Species:
Mouse
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Nsmce2
Format:
Viral Particles
Storage:
-80 °C
Human NSMCE2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_173685
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5158981
Datasheet
Catalog No. ABIN5158981
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
NCBI Accession:
NM_173685
Species:
Human
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of NSMCE2
Format:
Viral Particles
Storage:
-80 °C
Human NSMCE2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4836409
Datasheet
Catalog No. ABIN4836409
Type:
cDNA
Application:
Cloning
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
Species:
Human
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Insert length:
744 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human NSMCE2 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4622294
Datasheet
Catalog No. ABIN4622294
Type:
cDNA
Application:
Cloning
Gene:
Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
Species:
Human
Synonyms:
Nsmce2, NSMCE2, nsmce2.L, nse2
Insert length:
744 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC-GFP
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to NSMCE2

  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2)
  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2)
  • NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L)
  • Smc5-6 complex non-SMC subunit 2 (nse2)
  • 1110014D18Rik
  • AI661537
  • C8orf36
  • MMS21
  • Non-SMC element 2
  • NSE2
  • RGD1305156
  • ZMIZ7

Gene-IDs for different species

Protein level used designations for NSMCE2

  • E3 SUMO-protein ligase NSE2
  • MMS21 homolog
  • non-structural maintenance of chromosomes element 2 homolog
  • non-SMC element 2 homolog
  • hMMS21
  • methyl methanesulfonate sensitivity gene 21
  • zinc finger, MIZ-type containing 7
  • non-SMC element 2 homolog (MMS21, S. cerevisiae)
  • Non-structural maintenance of chromosomes element 2
Other products related to NSMCE2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
You are here:

antibodies-online

german

german (deutsch) antikoerper-online.de

english

english (english) antibodies-online.com

french

french (français) anticorps-enligne.fr

chinese

chinese (中文) antibodies-online.cn

genomics-online

english

english (english) genomics-online.com

Support