NSMCE2 (E3 SUMO-Protein Ligase NSE2, NSMCE2)
Short Description: E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
More information related to gene NSMCE2.
More information related to gene NSMCE2.
Products related to NSMCE2 Gene:
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64 results
OriGene rc207639l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- NCBI Accession:
- NM_173685,NP_775956
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5468670
$742.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc207639l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- NCBI Accession:
- NM_173685,NP_775956
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5468668
$742.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- E3 SUMO-Protein Ligase NSE2 (NSMCE2)
- NCBI Accession:
- NM_173685
- Gene ID:
- 286053 (Human, NSMCE2)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4937088
OriGene sr317290
RNAi
NSMCE2
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- E3 SUMO-Protein Ligase NSE2
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3314286
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to NSMCE2
- NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2)
- NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2)
- NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L)
- Smc5-6 complex non-SMC subunit 2 (nse2)
- 1110014D18Rik
- AI661537
- C8orf36
- MMS21
- Non-SMC element 2
- NSE2
- RGD1305156
- ZMIZ7
Gene-IDs for different species
Protein level used designations for NSMCE2
- E3 SUMO-protein ligase NSE2
- MMS21 homolog
- non-structural maintenance of chromosomes element 2 homolog
- non-SMC element 2 homolog
- hMMS21
- methyl methanesulfonate sensitivity gene 21
- zinc finger, MIZ-type containing 7
- non-SMC element 2 homolog (MMS21, S. cerevisiae)
- Non-structural maintenance of chromosomes element 2
Proteomics products related to NSMCE2 Gene
Other products related to NSMCE2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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