NSMCE2 (E3 SUMO-Protein Ligase NSE2, NSMCE2)
Short Description: E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
More information related to gene NSMCE2.
More information related to gene NSMCE2.
Products related to NSMCE2 Gene:
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64 results
OriGene kn407639
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3233750
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr406933
RNAi
NSMCE2
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- E3 SUMO-Protein Ligase NSE2
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3280894
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr507496
RNAi
NSMCE2
Species: Rat
HPLC purified
- Application:
- RNA Interference
- Gene:
- E3 SUMO-Protein Ligase NSE2
- Species:
- Rat
- Purification:
- HPLC purified
Catalog No. ABIN3356965
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene mc210732
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- NCBI Accession:
- NM_001164604,NP_001158076
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3332886
$163.35
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene mc210733
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- NCBI Accession:
- NM_026746,NP_081022
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3332887
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rn207782
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- NCBI Accession:
- NM_001024876,NP_001020047
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3332888
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc123332
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL5
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- NCBI Accession:
- NM_173685,NP_775956
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL5
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, T7 Promoter
- Expression:
- Transient
Catalog No. ABIN3391216
$297.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 2 to 4 Business Days
OriGene rg207639
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- E3 SUMO-Protein Ligase NSE2 (NSMCE2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5468665
$643.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc207639
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- NCBI Accession:
- NM_173685,NP_775956
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5468666
$445.50
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr207782
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae) (NSMCE2)
- NCBI Accession:
- NM_001024876,NP_001020047
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5468667
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to NSMCE2
- NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2)
- NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2)
- NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L)
- Smc5-6 complex non-SMC subunit 2 (nse2)
- 1110014D18Rik
- AI661537
- C8orf36
- MMS21
- Non-SMC element 2
- NSE2
- RGD1305156
- ZMIZ7
Gene-IDs for different species
Protein level used designations for NSMCE2
- E3 SUMO-protein ligase NSE2
- MMS21 homolog
- non-structural maintenance of chromosomes element 2 homolog
- non-SMC element 2 homolog
- hMMS21
- methyl methanesulfonate sensitivity gene 21
- zinc finger, MIZ-type containing 7
- non-SMC element 2 homolog (MMS21, S. cerevisiae)
- Non-structural maintenance of chromosomes element 2
Proteomics products related to NSMCE2 Gene
Other products related to NSMCE2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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