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p21 (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1), CDKN1A)

Short Description: This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010].
More information related to gene p21.

Products related to p21 Gene:

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92 results

Human CDKN1A cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene sc334388 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_001291549,NP_001278478
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322880
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human CDKN1A cDNA Clone in Mammalian Expression Vector
OriGene sc102496 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 3
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_078467,NP_510867
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3377422
$222.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Human CDKN1A cDNA Clone in Mammalian Expression Vector
OriGene sc119947 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 4
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_000389,NP_000380
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3383220
$222.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Human CDKN1A ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_078467
Gene ID:
1026 (Human, CDKN1A)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4920203
$99.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Details
Details
Human CDKN1A ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_001291549
Gene ID:
1026 (Human, CDKN1A)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4931606
$99.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human CDKN1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg201765 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_078467,NP_510867
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5398711
$420.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human CDKN1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg201817 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_000389,NP_000380
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5398712
$420.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human CDKN1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg231921 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_001220778,NP_001207707
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5398714
$346.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human CDKN1A ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc201765 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_078467,NP_510867
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5398715
$222.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human CDKN1A ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc236494 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_001291549,NP_001278478
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5398719
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pCMV6-XL5
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to p21

  • cyclin D1 (CCND1)
  • cyclin dependent kinase inhibitor 1A (CDKN1A)
  • cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a)
  • cyclin-dependent kinase inhibitor 1A (Cdkn1a)
  • cyclin-dependent kinase inhibitor 1A L homeolog (cdkn1a.L)
  • cyclin-dependent kinase inhibitor 1 (cki1)
  • cyclin-dependent kinase inhibitor 1A (cdkn1a)
  • cyclin dependent kinase inhibitor 1A (Cdkn1a)
  • KRAS proto-oncogene, GTPase (KRAS)
  • CAP20
  • cap20
  • CCND1
  • CDKI
  • CDKN1
  • Cdkn1
  • cdkn1
  • CDKN1A
  • CIP1
  • Cip1
  • cip1
  • KRAS2
  • MDA-6
  • mda-6
  • mda6
  • p16Xic2
  • P21
  • p21
  • p21CIP1
  • p21Cip1
  • p21cip1
  • p21ras
  • p21WAF
  • SDI1
  • sdi1
  • si:ch1073-48m5.2
  • UV96
  • WAF1
  • Waf1
  • waf1

Gene-IDs for different species

Protein level used designations for p21

  • cyclin D1
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  • CDK-interacting protein 1
  • CDK-interaction protein 1
  • DNA synthesis inhibitor
  • cyclin-dependent kinase inhibitor 1
  • melanoma differentiation associated protein 6
  • wild-type p53-activated fragment 1
  • melanoma differentiation-associated protein
  • p21
  • cyclin-dependent kinase inhibitor 1A (P21)
  • cyclin dependent kinase inhibitor p16Xic2
  • cip1
  • p21
  • waf1
  • cyclin-dependent kinase inhibitor 1A
  • p21/WAF1
  • GTPase KRas
  • Kirsten rat sarcoma viral (Kras-2) oncogene homolog
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Other products related to p21 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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