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p21 (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1), CDKN1A)

Short Description: This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010].
More information related to gene p21.

Products related to p21 Gene:

92 results :

Human CDKN1A ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739620
Datasheet
Catalog No. ABIN5739620
Type:
ORF
Application:
Cloning
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
Species:
Human
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Insert length:
495 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CDKN1A ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5739621
Datasheet
Catalog No. ABIN5739621
Type:
ORF
Application:
Cloning
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
Species:
Human
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Insert length:
495 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human CDKN1A cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4473842
Datasheet
Catalog No. ABIN4473842
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
Species:
Human
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Insert length:
495 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human CDKN1A cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4473841
Datasheet
Catalog No. ABIN4473841
Type:
cDNA
Application:
Protein Expression
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
Species:
Human
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Insert length:
495 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat CDKN1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_080782
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232526
Datasheet
Catalog No. ABIN5232526
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_080782
Species:
Rat
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cdkn1a
Format:
Viral Particles
Storage:
-80 °C
Rat CDKN1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_080782
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232524
Datasheet
Catalog No. ABIN5232524
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_080782
Species:
Rat
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cdkn1a
Format:
Viral Particles
Storage:
-80 °C
Rat CDKN1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_080782
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232525
Datasheet
Catalog No. ABIN5232525
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_080782
Species:
Rat
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cdkn1a
Format:
Viral Particles
Storage:
-80 °C
Mouse CDKN1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_007669
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232522
Datasheet
Catalog No. ABIN5232522
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_007669
Species:
Mouse
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cdkn1a
Format:
Viral Particles
Storage:
-80 °C
Human CDKN1A CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_000389
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5232520
Datasheet
Catalog No. ABIN5232520
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_000389
Species:
Human
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of CDKN1A
Format:
Viral Particles
Storage:
-80 °C
Rat CDKN1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_080782
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5117170
Datasheet
Catalog No. ABIN5117170
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A)
NCBI Accession:
NM_080782
Species:
Rat
Synonyms:
CCND1, CDKN1A, Cdkn1a, cdkn1a.L, cki1, cdkn1a, KRAS
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Cdkn1a
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL4
    • pCMV6-XL5
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to p21

  • cyclin D1 (CCND1)
  • cyclin dependent kinase inhibitor 1A (CDKN1A)
  • cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a)
  • cyclin-dependent kinase inhibitor 1A (Cdkn1a)
  • cyclin-dependent kinase inhibitor 1A L homeolog (cdkn1a.L)
  • cyclin-dependent kinase inhibitor 1 (cki1)
  • cyclin-dependent kinase inhibitor 1A (cdkn1a)
  • cyclin dependent kinase inhibitor 1A (Cdkn1a)
  • KRAS proto-oncogene, GTPase (KRAS)
  • CAP20
  • cap20
  • CCND1
  • CDKI
  • CDKN1
  • Cdkn1
  • cdkn1
  • CDKN1A
  • CIP1
  • Cip1
  • cip1
  • KRAS2
  • MDA-6
  • mda-6
  • mda6
  • p16Xic2
  • P21
  • p21
  • p21CIP1
  • p21Cip1
  • p21cip1
  • p21ras
  • p21WAF
  • SDI1
  • sdi1
  • si:ch1073-48m5.2
  • UV96
  • WAF1
  • Waf1
  • waf1

Gene-IDs for different species

Protein level used designations for p21

  • cyclin D1
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  • CDK-interacting protein 1
  • CDK-interaction protein 1
  • DNA synthesis inhibitor
  • cyclin-dependent kinase inhibitor 1
  • melanoma differentiation associated protein 6
  • wild-type p53-activated fragment 1
  • melanoma differentiation-associated protein
  • p21
  • cyclin-dependent kinase inhibitor 1A (P21)
  • cyclin dependent kinase inhibitor p16Xic2
  • cip1
  • p21
  • waf1
  • cyclin-dependent kinase inhibitor 1A
  • p21/WAF1
  • GTPase KRas
  • Kirsten rat sarcoma viral (Kras-2) oncogene homolog
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Other products related to p21 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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