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Parkin (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin), PARK2)

Short Description: The precise function of this gene is unknown\; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008].
More information related to gene Parkin.

Products related to Parkin Gene:

75 results :

Human PARK2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5755496
Datasheet
Catalog No. ABIN5755496
Type:
ORF
Application:
Cloning
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
Species:
Human
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Insert length:
1164 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PARK2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4479110
Datasheet
Catalog No. ABIN4479110
Type:
cDNA
Application:
Protein Expression
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
Species:
Human
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Insert length:
1164 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat PARK2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_020093
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4467915
Datasheet
Catalog No. ABIN4467915
Type:
cDNA
Application:
Protein Expression
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_020093
Species:
Rat
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Insert length:
1053 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PARK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_016694
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263602
Datasheet
Catalog No. ABIN5263602
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_016694
Species:
Mouse
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Park2
Format:
Viral Particles
Storage:
-80 °C
Mouse PARK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_016694
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263603
Datasheet
Catalog No. ABIN5263603
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_016694
Species:
Mouse
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Park2
Format:
Viral Particles
Storage:
-80 °C
Mouse PARK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_016694
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263601
Datasheet
Catalog No. ABIN5263601
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_016694
Species:
Mouse
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Park2
Format:
Viral Particles
Storage:
-80 °C
Human PARK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_004562
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263597
Datasheet
Catalog No. ABIN5263597
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_004562
Species:
Human
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PARK2
Format:
Viral Particles
Storage:
-80 °C
Human PARK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_004562
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263599
Datasheet
Catalog No. ABIN5263599
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_004562
Species:
Human
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PARK2
Format:
Viral Particles
Storage:
-80 °C
Human PARK2 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_004562
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5263598
Datasheet
Catalog No. ABIN5263598
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_004562
Species:
Human
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PARK2
Format:
Viral Particles
Storage:
-80 °C
Mouse PARK2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_016694
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5148068
Datasheet
Catalog No. ABIN5148068
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2)
NCBI Accession:
NM_016694
Species:
Mouse
Synonyms:
park, PRKN, Prkn, prkn, CpipJ_CPIJ014867, Park2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Park2
Format:
Viral Particles
Storage:
-80 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
    • pCas-Guide
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
  • Format
    • Lyophilized
    • Viral Particles
    • Liquid

Synonyms and alternative names related to Parkin

  • parkin (park)
  • parkin RBR E3 ubiquitin protein ligase (PRKN)
  • parkin RBR E3 ubiquitin protein ligase (Prkn)
  • parkin RBR E3 ubiquitin protein ligase (prkn)
  • parkin (CpipJ_CPIJ014867)
  • Parkinson disease (autosomal recessive, juvenile) 2, parkin (Park2)
  • AR-JP
  • CG10523
  • Dmel\\CG10523
  • Dpark
  • dpk
  • LPRS2
  • Park
  • PARK2
  • PDJ
  • pdr-1
  • PRKN
  • Prkn
  • SD01679
  • si:ch211-123f21.1
  • zgc:112390

Gene-IDs for different species

Protein level used designations for Parkin

  • CG10523-PB
  • CG10523-PC
  • D-parkin
  • dparkin
  • park-PB
  • park-PC
  • E3 ubiquitin-protein ligase parkin
  • Parkinson disease (autosomal recessive, juvenile) 2, parkin
  • parkinson juvenile disease protein 2
  • parkin variant SV5DEL
  • parkin
  • parkin protein
  • parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Other products related to Parkin such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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