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PDE6B (phosphodiesterase 6B, CGMP-Specific, Rod, beta, PDE6B)

Short Description: Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].
More information related to gene PDE6B.

Products related to PDE6B Gene:

64 results :

Human PDE6B ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756709
Datasheet
Catalog No. ABIN5756709
Type:
ORF
Application:
Cloning
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
Species:
Human
Synonyms:
PDE6B, Pde6b
Insert length:
2562 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PDE6B cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4479216
Datasheet
Catalog No. ABIN4479216
Type:
cDNA
Application:
Protein Expression
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
Species:
Human
Synonyms:
PDE6B, Pde6b
Insert length:
2562 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat PDE6B CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_001106024
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265819
Datasheet
Catalog No. ABIN5265819
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_001106024
Species:
Rat
Synonyms:
PDE6B, Pde6b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pde6b
Format:
Viral Particles
Storage:
-80 °C
Human PDE6B CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_000283
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265815
Datasheet
Catalog No. ABIN5265815
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_000283
Species:
Human
Synonyms:
PDE6B, Pde6b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PDE6B
Format:
Viral Particles
Storage:
-80 °C
Mouse PDE6B CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_008806
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5265817
Datasheet
Catalog No. ABIN5265817
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_008806
Species:
Mouse
Synonyms:
PDE6B, Pde6b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pde6b
Format:
Viral Particles
Storage:
-80 °C
Rat PDE6B CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_001106024
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150269
Datasheet
Catalog No. ABIN5150269
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_001106024
Species:
Rat
Synonyms:
PDE6B, Pde6b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pde6b
Format:
Viral Particles
Storage:
-80 °C
Mouse PDE6B CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_008806
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150267
Datasheet
Catalog No. ABIN5150267
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_008806
Species:
Mouse
Synonyms:
PDE6B, Pde6b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Pde6b
Format:
Viral Particles
Storage:
-80 °C
Human PDE6B CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_000283
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150265
Datasheet
Catalog No. ABIN5150265
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
NCBI Accession:
NM_000283
Species:
Human
Synonyms:
PDE6B, Pde6b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PDE6B
Format:
Viral Particles
Storage:
-80 °C
Human PDE6B cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4837255
Datasheet
Catalog No. ABIN4837255
Type:
cDNA
Application:
Cloning
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
Species:
Human
Synonyms:
PDE6B, Pde6b
Insert length:
2562 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PDE6B cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4622687
Datasheet
Catalog No. ABIN4622687
Type:
cDNA
Application:
Cloning
Gene:
phosphodiesterase 6B, CGMP-Specific, Rod, beta (PDE6B)
Species:
Human
Synonyms:
PDE6B, Pde6b
Insert length:
2562 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-XL4
    • pCMV6-XL5
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PDE6B

  • phosphodiesterase 6B (PDE6B)
  • phosphodiesterase 6B (Pde6b)
  • phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide (Pde6b)
  • CSNB3
  • CSNBAD2
  • PDBS
  • PDEB
  • Pdeb
  • r
  • RCD-1
  • rd
  • rd-1
  • rd1
  • rd10
  • RP40

Gene-IDs for different species

Protein level used designations for PDE6B

  • GMP-PDE beta
  • rod cGMP-phosphodiesterase beta-subunit
  • rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
  • pde6B gene for cGMP phosphodiesterase beta subunit
  • phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant)
  • rod cGMP phosphodiesterase beta subunit
  • phosphodiesterase, cyclic GMP ( rod receptor), beta polypeptide
  • phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
  • cGMP-phosphodiesterase beta-subunit
  • phosphodiesterase, cGMP, rod receptor, beta polypeptide
  • retinal degeneration 1
Other products related to PDE6B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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