PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1, PDHA1)
Short Description: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010].
More information related to gene PDHA1.
More information related to gene PDHA1.
Products related to PDHA1 Gene:
Recommended next Filters:
69 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- NCBI Accession:
- NM_054055
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- NCBI Accession:
- NM_001004072
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- NCBI Accession:
- NM_000284
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1)
- NCBI Accession:
- NM_008810
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Synonyms and alternative names related to PDHA1
- pyruvate dehydrogenase E1 alpha 1 subunit (PDHA1)
- pyruvate dehydrogenase E1 alpha 1 (Pdha1)
- pyruvate dehydrogenase E1 alpha 1 subunit (Pdha1)
- pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1)
- pyruvate dehydrogenase E1 alpha 1 subunit (pdha1)
- pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene (LOC719277)
- 2-oxo acid dehydrogenase (VNG_RS07485)
- pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha (RR_RS04695)
- pyruvate dehydrogenase alpha subunit protein (pdhA1)
- pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit (pdhA1)
- precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit (PDHA1)
- pyruvate dehydrogenase (PDHA1)
- pyruvate dehydrogenase E1 alpha 1 subunit a (pdha1a)
- pyruvate dehydrogenase E1 alpha 1 subunit b (pdha1b)
- pyruvate dehydrogenase E1 component subunit alpha (NI36_RS05240)
- pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog (pdha1.S)
- im:6895726
- NI36_05250
- PDHA
- pdha
- Pdha-1
- pdha1
- Pdha1
- pdha1-a
- pdha1-b
- PDHCE1A
- pdhce1a
- PHE1A
- phe1a
- wu:fd18b01
- wu:fo96f03
- wu:fp73b04
- zgc:73271
- zgc:86692
- zgc:92705
Gene-IDs for different species
Protein level used designations for PDHA1
- PDHE1-A type I
- pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- pyruvate dehydrogenase complex, E1-alpha polypeptide 1
- pyruvate dehydrogenase E1alpha subunit
- pyruvate dehydrogenase E1 alpha 1
- pyruvate dehydrogenase E1 component alpha subunit
- pyruvate dehydrogenase alpha 1
- pyruvate dehydrogenase (lipoamide) alpha 1
- PdhA1
- pyruvate dehydrogenase alpha subunit
- pyruvate dehydrogenase E1 component subunit alpha
- pyruvate dehydrogenase alpha subunit protein
- pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit
- precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit
- pyruvate dehydrogenase
- Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
- pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like
- fp73b04
- pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog
Proteomics products related to PDHA1 Gene
Other products related to PDHA1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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