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PDP (Pyruvate Dehydrogenase Phosphatase, PDP)

Short Description: Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported\; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009].
More information related to gene PDP.

Products related to PDP Gene:

70 results

ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Gene ID:
54704 (Human, PDP)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5324076
$235.38
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 19 Business Days
OriGene tg302335 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3727250
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tg508610 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3690633
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tl302335 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3747588
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tr302335 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3767927
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tf508610 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3670935
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tr508610 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3540939
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tl710366 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3447647
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tg710366 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3504574
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tl508610 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3521223
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • HA tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-XL5
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pRS
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PDP

  • Pyruvate dehydrogenase phosphatase (Pdp)
  • pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial (LOC413080)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (Pdp1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (pdp1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog (pdp1.L)
  • 153332_at
  • CG12151
  • Dmel\\CG12151
  • Gm1024
  • im:7157162
  • PDH
  • PDP
  • pdp
  • pdp1
  • PDPC
  • PPM2C
  • Ppm2c
  • ppm2c
  • zgc:174908

Gene-IDs for different species

Protein level used designations for PDP

  • CG12151-PA
  • CG12151-PB
  • Pdp-PA
  • Pdp-PB
  • pyruvate dehydrogenase phosphatase
  • PDP 1
  • PDPC 1
  • [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
  • protein phosphatase 2C, magnesium-dependent, catalytic subunit
  • pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase
  • pyruvate dehydrogenase phosphatase catalytic subunit 1
  • protein phosphatase 2C, magnesium dependent, catalytic subunit
  • pyruvate dehydrogenase phosphatase isoenzyme 2
  • pyruvate dehydrogenase phosphatase isoenzyme 1
  • pyruvate dehydrogenase phosphatase, catalytic subunit 1
  • pyruvate dehyrogenase phosphatase catalytic subunit 1
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog
Other products related to PDP such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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