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PDP (Pyruvate Dehydrogenase Phosphatase, PDP)

Short Description: Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported\; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009].
More information related to gene PDP.

Products related to PDP Gene:

70 results

OriGene tr710366 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3435256
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene kn513060 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3230233
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn408198 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3230232
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sr416963 RNAi PDP Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3264499
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sc327115 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001161778,NP_001155250
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322713
$604.89
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc327582 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001161781,NP_001155253
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322714
$545.49
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc218699 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001033453,NP_001028625
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3363938
$546.48
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc219138 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001098230,NP_001091700
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3363939
$519.75
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene mc219246 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001098231,NP_001091701
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3363940
$583.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene mc228319 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001290391,NP_001277320
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3363941
$571.23
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • HA tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-XL5
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pRS
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PDP

  • Pyruvate dehydrogenase phosphatase (Pdp)
  • pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial (LOC413080)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (Pdp1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (pdp1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog (pdp1.L)
  • 153332_at
  • CG12151
  • Dmel\\CG12151
  • Gm1024
  • im:7157162
  • PDH
  • PDP
  • pdp
  • pdp1
  • PDPC
  • PPM2C
  • Ppm2c
  • ppm2c
  • zgc:174908

Gene-IDs for different species

Protein level used designations for PDP

  • CG12151-PA
  • CG12151-PB
  • Pdp-PA
  • Pdp-PB
  • pyruvate dehydrogenase phosphatase
  • PDP 1
  • PDPC 1
  • [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
  • protein phosphatase 2C, magnesium-dependent, catalytic subunit
  • pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase
  • pyruvate dehydrogenase phosphatase catalytic subunit 1
  • protein phosphatase 2C, magnesium dependent, catalytic subunit
  • pyruvate dehydrogenase phosphatase isoenzyme 2
  • pyruvate dehydrogenase phosphatase isoenzyme 1
  • pyruvate dehydrogenase phosphatase, catalytic subunit 1
  • pyruvate dehyrogenase phosphatase catalytic subunit 1
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog
Other products related to PDP such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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