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PDP (Pyruvate Dehydrogenase Phosphatase, PDP)

Short Description: Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported\; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009].
More information related to gene PDP.

Products related to PDP Gene:

70 results

OriGene mc228358 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001290387,NP_001277316
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3363942
$587.07
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rn216919 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001271108,NP_001258037
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3363944
$571.23
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rn214424 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_019372,NP_062245
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3363943
$546.48
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc128049 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_018444,NP_060914
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3385737
$495.99
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sc327091 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Pubmed 1
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001161779,NP_001155251
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3391440
$570.24
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sc327092 cDNA PExp Mammalian Expression Vector pCMV6-XL5 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001161780,NP_001155252
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL5
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3391441
$570.24
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001161781
Gene ID:
54704 (Human, PDP)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4918624
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
OriGene rr214424 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_019372,NP_062245
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5462995
$545.49
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Pyruvate Dehydrogenase Phosphatase (PDP)
NCBI Accession:
NM_001161780
Gene ID:
54704 (Human, PDP)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925657
$469.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene sr310197 RNAi PDP Species: Human HPLC purified
Application:
RNA Interference
Gene:
Pyruvate Dehydrogenase Phosphatase
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3286232
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • His tag
    • GFP tag
    • HA tag
    • Myc-DYKDDDDK Tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pCMV6-XL5
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pRS
    • pCas-Guide
    • pcDNA3.1+C-(K)-DYK
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • Enhanced CMV Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PDP

  • Pyruvate dehydrogenase phosphatase (Pdp)
  • pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial (LOC413080)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (Pdp1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 (pdp1)
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog (pdp1.L)
  • 153332_at
  • CG12151
  • Dmel\\CG12151
  • Gm1024
  • im:7157162
  • PDH
  • PDP
  • pdp
  • pdp1
  • PDPC
  • PPM2C
  • Ppm2c
  • ppm2c
  • zgc:174908

Gene-IDs for different species

Protein level used designations for PDP

  • CG12151-PA
  • CG12151-PB
  • Pdp-PA
  • Pdp-PB
  • pyruvate dehydrogenase phosphatase
  • PDP 1
  • PDPC 1
  • [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
  • protein phosphatase 2C, magnesium-dependent, catalytic subunit
  • pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase
  • pyruvate dehydrogenase phosphatase catalytic subunit 1
  • protein phosphatase 2C, magnesium dependent, catalytic subunit
  • pyruvate dehydrogenase phosphatase isoenzyme 2
  • pyruvate dehydrogenase phosphatase isoenzyme 1
  • pyruvate dehydrogenase phosphatase, catalytic subunit 1
  • pyruvate dehyrogenase phosphatase catalytic subunit 1
  • pyruvate dehyrogenase phosphatase catalytic subunit 1 L homeolog
Other products related to PDP such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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