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PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A, PPM1A)

Short Description: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
More information related to gene PPM1A.

Products related to PPM1A Gene:

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67 results

Human PPM1A cDNA Clone in Mammalian Expression Vector
OriGene sc321896 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_021003,NP_066283
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3319210
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Rat PPM1A siRNA Oligo
OriGene sr511053 RNAi PPM1A Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3360018
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Rat PPM1A cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rn211341 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_017038,NP_058734
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3365358
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human PPM1A cDNA Clone in Mammalian Expression Vector
OriGene sc127980 cDNA PExp Mammalian Expression Vector pCMV6-XL4 Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_177952,NP_808821
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-XL4
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter, T7 Promoter
Expression:
Transient
Catalog No. ABIN3379502
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Human PPM1A ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_021003
Gene ID:
5494 (Human, PPM1A)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4936417
$319.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Details
Details
Human PPM1A ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_177951
Gene ID:
5494 (Human, PPM1A)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925200
$309.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human PPM1A ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_177952
Gene ID:
5494 (Human, PPM1A)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925201
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human PPM1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg218055 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5454984
$495.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human PPM1A ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg202070 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5454982
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human PPM1A ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc218055 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_177951,NP_808820
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5454988
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-XL4
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PPM1A

  • protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Ab (ppm1ab)
  • protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1A (Ppm1a)
  • protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog (ppm1a.L)
  • protein phosphatase, Mg2+/Mn2+ dependent 1A (Ppm1a)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Aa (ppm1aa)
  • 2310003C21Rik
  • 2900017D14Rik
  • AI427932
  • AU017636
  • MMPa-2
  • MPPa-1
  • PP2C-ALPHA
  • pp2c-alpha
  • Pp2c1
  • PP2CA
  • pp2ca
  • pp2ca1
  • pp2ca2
  • PP2Calpha
  • pp2calpha
  • ppp1r13b
  • si:ch211-253p18.1
  • wu:fd42g12
  • zgc:153820

Gene-IDs for different species

Protein level used designations for PPM1A

  • protein phosphatase 1A
  • protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform
  • protein phosphatase type 2C alpha 1
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B
  • Mpp alpha
  • PP2C-alpha
  • protein phosphatase 2C isoform alpha
  • protein phosphatase IA
  • IA
  • Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform
  • Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform
  • protein phosphatase 1A, magnesium dependent, alpha isoform
  • protein phosphatase 2C alpha
  • protein phosphatase type 2C alpha 2
Other products related to PPM1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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