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PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A, PPM1A)

Short Description: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
More information related to gene PPM1A.

Products related to PPM1A Gene:

67 results :

Human PPM1A ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756883
Datasheet
Catalog No. ABIN5756883
Type:
ORF
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Insert length:
1149 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PPM1A cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4479690
Datasheet
Catalog No. ABIN4479690
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Insert length:
1149 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat PPM1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_017038
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150637
Datasheet
Catalog No. ABIN5150637
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_017038
Species:
Rat
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ppm1a
Format:
Viral Particles
Storage:
-80 °C
Mouse PPM1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_008910
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150635
Datasheet
Catalog No. ABIN5150635
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_008910
Species:
Mouse
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ppm1a
Format:
Viral Particles
Storage:
-80 °C
Human PPM1A CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_177952
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150633
Datasheet
Catalog No. ABIN5150633
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_177952
Species:
Human
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PPM1A
Format:
Viral Particles
Storage:
-80 °C
Human PPM1A cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4837979
Datasheet
Catalog No. ABIN4837979
Type:
cDNA
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Insert length:
1149 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PPM1A cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4623161
Datasheet
Catalog No. ABIN4623161
Type:
cDNA
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Insert length:
1149 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PPM1A cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4414605
Datasheet
Catalog No. ABIN4414605
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Insert length:
1149 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PPM1A cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4708849
Datasheet
Catalog No. ABIN4708849
Type:
cDNA
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
Species:
Human
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Insert length:
1149 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PPM1A ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_008910
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5756884
Datasheet
Catalog No. ABIN5756884
Type:
ORF
Application:
Cloning
Gene:
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
NCBI Accession:
NM_008910
Species:
Mouse
Synonyms:
PPM1A, ppm1ab, Ppm1a, ppm1a.L, ppm1aa
Insert length:
1149 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-XL4
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • gRNA + Cas9
    • shRNA
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PPM1A

  • protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Ab (ppm1ab)
  • protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1A (Ppm1a)
  • protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog (ppm1a.L)
  • protein phosphatase, Mg2+/Mn2+ dependent 1A (Ppm1a)
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Aa (ppm1aa)
  • 2310003C21Rik
  • 2900017D14Rik
  • AI427932
  • AU017636
  • MMPa-2
  • MPPa-1
  • PP2C-ALPHA
  • pp2c-alpha
  • Pp2c1
  • PP2CA
  • pp2ca
  • pp2ca1
  • pp2ca2
  • PP2Calpha
  • pp2calpha
  • ppp1r13b
  • si:ch211-253p18.1
  • wu:fd42g12
  • zgc:153820

Gene-IDs for different species

Protein level used designations for PPM1A

  • protein phosphatase 1A
  • protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform
  • protein phosphatase type 2C alpha 1
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B
  • Mpp alpha
  • PP2C-alpha
  • protein phosphatase 2C isoform alpha
  • protein phosphatase IA
  • IA
  • Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform
  • Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform
  • protein phosphatase 1A, magnesium dependent, alpha isoform
  • protein phosphatase 2C alpha
  • protein phosphatase type 2C alpha 2
Other products related to PPM1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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