PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A, PPM1A)
Short Description: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
More information related to gene PPM1A.
More information related to gene PPM1A.
Products related to PPM1A Gene:
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67 results
OriGene tf709852
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3490131
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tl709852
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3447135
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg709852
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3504062
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr501720
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3534063
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr709852
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3443249
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sr412881
RNAi
PPM1A
Species: Mouse
HPLC purified
- Application:
- RNA Interference
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A
- Species:
- Mouse
- Purification:
- HPLC purified
Catalog No. ABIN3268963
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene sc327866
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- NCBI Accession:
- NM_177952,NP_808821
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3304100
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sc312956
cDNA
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- NCBI Accession:
- NM_177951,NP_808820
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- Enhanced CMV Promoter
- Expression:
- Transient
Catalog No. ABIN3304099
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn513708
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Mouse
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3231557
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene kn402070
gRNA + Cas9
GEEN
Mammalian Expression Vector
pCas-Guide
Ampicillin
U6 Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- gRNA + Cas9
- Application:
- Genome Editing with Engineered Nucleases
- Gene:
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCas-Guide
- Resistance Gene:
- Ampicillin
- Promoter:
- U6 Promoter, Enhanced CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN3231556
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 21 to 22 Business Days
Synonyms and alternative names related to PPM1A
- protein phosphatase, Mg2+/Mn2+ dependent 1A (PPM1A)
- protein phosphatase, Mg2+/Mn2+ dependent, 1Ab (ppm1ab)
- protein phosphatase 1A, magnesium dependent, alpha isoform (Ppm1a)
- protein phosphatase, Mg2+/Mn2+ dependent, 1A (Ppm1a)
- protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog (ppm1a.L)
- protein phosphatase, Mg2+/Mn2+ dependent 1A (Ppm1a)
- protein phosphatase, Mg2+/Mn2+ dependent, 1Aa (ppm1aa)
- 2310003C21Rik
- 2900017D14Rik
- AI427932
- AU017636
- MMPa-2
- MPPa-1
- PP2C-ALPHA
- pp2c-alpha
- Pp2c1
- PP2CA
- pp2ca
- pp2ca1
- pp2ca2
- PP2Calpha
- pp2calpha
- ppp1r13b
- si:ch211-253p18.1
- wu:fd42g12
- zgc:153820
Gene-IDs for different species
Protein level used designations for PPM1A
- protein phosphatase 1A
- protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform
- protein phosphatase type 2C alpha 1
- protein phosphatase 1, regulatory (inhibitor) subunit 13B
- Mpp alpha
- PP2C-alpha
- protein phosphatase 2C isoform alpha
- protein phosphatase IA
- IA
- Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform
- Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform
- protein phosphatase 1A, magnesium dependent, alpha isoform
- protein phosphatase 2C alpha
- protein phosphatase type 2C alpha 2
Proteomics products related to PPM1A Gene
Other products related to PPM1A such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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