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PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta, PRKAR2B)

Short Description: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq, Jul 2008].
More information related to gene PRKAR2B.

Products related to PRKAR2B Gene:

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53 results

Rat PRKAR2B shRNA in Lentiviral Vector (GFP tag)
OriGene tl703111 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3511269
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse PRKAR2B siRNA Oligo
OriGene sr413804 RNAi PRKAR2B Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3269879
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse PRKAR2B CRISPR gRNA + Cas9 in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene kn513879 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3231918
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human PRKAR2B CRISPR gRNA + Cas9 in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene kn409900 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3231917
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Rat PRKAR2B siRNA Oligo
OriGene sr505262 RNAi PRKAR2B Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3355052
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human PRKAR2B cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene sc125501 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Pubmed 2
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_002736,NP_002727
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3322823
$679.14
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
Details
Details
Mouse PRKAR2B cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene mc209226 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_011158,NP_035288
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3365714
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
Details
Details
Rat PRKAR2B cDNA Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rn205548 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_001030020,NP_001025191
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3365715
$497.97
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 31 to 32 Business Days
Details
Details
Human PRKAR2B ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_002736
Gene ID:
5577 (Human, PRKAR2B)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4925055
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
Details
Details
Human PRKAR2B ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg209900 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5395229
$877.14
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pCMV6-AC-GFP
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PRKAR2B

  • protein kinase, cAMP-dependent, regulatory subunit type II beta S homeolog (prkar2b.S)
  • protein kinase cAMP-dependent type II regulatory subunit beta (PRKAR2B)
  • protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B)
  • protein kinase cAMP-dependent type II regulatory subunit beta (prkar2b)
  • protein kinase, cAMP dependent regulatory, type II beta (Prkar2b)
  • protein kinase cAMP-dependent type 2 regulatory subunit beta (Prkar2b)
  • AI451071
  • AW061005
  • MGC83177
  • Pkarb2
  • PKARIIbeta
  • PRKAR2
  • PRKAR2B
  • RATDNA
  • RII(beta)
  • RII-BETA

Gene-IDs for different species

Protein level used designations for PRKAR2B

  • protein kinase, cAMP-dependent, regulatory, type II, beta
  • cAMP-dependent protein kinase, regulatory subunit beta 2
  • cAMP-dependent protein kinase type II-beta regulatory subunit-like
  • protein kinase, cAMP dependent regulatory, type II beta
  • cAMP-dependent protein kinase type II-beta regulatory subunit
  • Type II beta regulatory subunit of cAMP-dependent protein kinase
  • H_RG363E19.2
  • WUGSC:H_RG363E19.2
  • cAMP-dependent protein kinase type II-beta regulatory chain
Other products related to PRKAR2B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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