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PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta, PRKAR2B)

Short Description: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq, Jul 2008].
More information related to gene PRKAR2B.

Products related to PRKAR2B Gene:

53 results :

Human PRKAR2B ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738622
Datasheet
Catalog No. ABIN5738622
Type:
ORF
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Insert length:
1257 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PRKAR2B cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4479794
Datasheet
Catalog No. ABIN4479794
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Insert length:
1257 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PRKAR2B CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_011158
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115262
Datasheet
Catalog No. ABIN5115262
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_011158
Species:
Mouse
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Prkar2b
Format:
Viral Particles
Storage:
-80 °C
Human PRKAR2B CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_002736
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115260
Datasheet
Catalog No. ABIN5115260
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_002736
Species:
Human
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PRKAR2B
Format:
Viral Particles
Storage:
-80 °C
Rat PRKAR2B CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_001030020
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5115264
Datasheet
Catalog No. ABIN5115264
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_001030020
Species:
Rat
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Prkar2b
Format:
Viral Particles
Storage:
-80 °C
Human PRKAR2B cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4838151
Datasheet
Catalog No. ABIN4838151
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Insert length:
1257 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PRKAR2B cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4623265
Datasheet
Catalog No. ABIN4623265
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Insert length:
1257 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PRKAR2B cDNA Clone in Mammalian Expression Vector (His tag)
cDNA PExp Mammalian Expression Vector pPM-C-His Kanamycin CMV Promoter His tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Catalog No. ABIN4414708
Datasheet
Catalog No. ABIN4414708
Type:
cDNA
Application:
Protein Expression
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Insert length:
1257 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PRKAR2B cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4709021
Datasheet
Catalog No. ABIN4709021
Type:
cDNA
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
Species:
Human
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Insert length:
1257 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PRKAR2B ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_011158
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5738623
Datasheet
Catalog No. ABIN5738623
Type:
ORF
Application:
Cloning
Gene:
Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
NCBI Accession:
NM_011158
Species:
Mouse
Synonyms:
prkar2b.S, PRKAR2B, prkar2b, Prkar2b
Insert length:
1251 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pCMV6-AC-GFP
    • pDONR223
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • ORF
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PRKAR2B

  • protein kinase, cAMP-dependent, regulatory subunit type II beta S homeolog (prkar2b.S)
  • protein kinase cAMP-dependent type II regulatory subunit beta (PRKAR2B)
  • protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B)
  • protein kinase cAMP-dependent type II regulatory subunit beta (prkar2b)
  • protein kinase, cAMP dependent regulatory, type II beta (Prkar2b)
  • protein kinase cAMP-dependent type 2 regulatory subunit beta (Prkar2b)
  • AI451071
  • AW061005
  • MGC83177
  • Pkarb2
  • PKARIIbeta
  • PRKAR2
  • PRKAR2B
  • RATDNA
  • RII(beta)
  • RII-BETA

Gene-IDs for different species

Protein level used designations for PRKAR2B

  • protein kinase, cAMP-dependent, regulatory, type II, beta
  • cAMP-dependent protein kinase, regulatory subunit beta 2
  • cAMP-dependent protein kinase type II-beta regulatory subunit-like
  • protein kinase, cAMP dependent regulatory, type II beta
  • cAMP-dependent protein kinase type II-beta regulatory subunit
  • Type II beta regulatory subunit of cAMP-dependent protein kinase
  • H_RG363E19.2
  • WUGSC:H_RG363E19.2
  • cAMP-dependent protein kinase type II-beta regulatory chain
Other products related to PRKAR2B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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