PRKAR2B (Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta, PRKAR2B)
Short Description: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq, Jul 2008].
More information related to gene PRKAR2B.
More information related to gene PRKAR2B.
Products related to PRKAR2B Gene:
Recommended next Filters:
53 results
OriGene rc209900
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
- NCBI Accession:
- NM_002736,NP_002727
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5395230
$679.14
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr205548
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta (PRKAR2B)
- NCBI Accession:
- NM_001030020,NP_001025191
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5395231
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 31 to 32 Business Days
OriGene sr303734
RNAi
PRKAR2B
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Protein Kinase, CAMP-Dependent, Regulatory, Type II, beta
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3343509
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to PRKAR2B
- protein kinase, cAMP-dependent, regulatory subunit type II beta S homeolog (prkar2b.S)
- protein kinase cAMP-dependent type II regulatory subunit beta (PRKAR2B)
- protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B)
- protein kinase cAMP-dependent type II regulatory subunit beta (prkar2b)
- protein kinase, cAMP dependent regulatory, type II beta (Prkar2b)
- protein kinase cAMP-dependent type 2 regulatory subunit beta (Prkar2b)
- AI451071
- AW061005
- MGC83177
- Pkarb2
- PKARIIbeta
- PRKAR2
- PRKAR2B
- RATDNA
- RII(beta)
- RII-BETA
Gene-IDs for different species
Protein level used designations for PRKAR2B
- protein kinase, cAMP-dependent, regulatory, type II, beta
- cAMP-dependent protein kinase, regulatory subunit beta 2
- cAMP-dependent protein kinase type II-beta regulatory subunit-like
- protein kinase, cAMP dependent regulatory, type II beta
- cAMP-dependent protein kinase type II-beta regulatory subunit
- Type II beta regulatory subunit of cAMP-dependent protein kinase
- H_RG363E19.2
- WUGSC:H_RG363E19.2
- cAMP-dependent protein kinase type II-beta regulatory chain
Proteomics products related to PRKAR2B Gene
Other products related to PRKAR2B such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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