PSMC2 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2, PSMC2)
Short Description: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2011].
More information related to gene PSMC2.
More information related to gene PSMC2.
Products related to PSMC2 Gene:
Recommended next Filters:
60 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- NCBI Accession:
- NM_002803
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- NCBI Accession:
- NM_033236
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- NCBI Accession:
- NM_011188
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- NCBI Accession:
- NM_033236
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- NCBI Accession:
- NM_011188
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- NCBI Accession:
- NM_002803
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
Synonyms and alternative names related to PSMC2
- proteasome 26S subunit, ATPase 2 L homeolog (psmc2.L)
- proteasome (prosome, macropain) 26S subunit, ATPase 2 (psmc2)
- 26S protease regulatory subunit 7 (psmC2)
- proteasome 26S subunit, ATPase 2 (PSMC2)
- regulatory particle, ATPase-like-1 (rpt-1)
- 26S protease regulatory subunit 7 (GL50803_21331)
- 26S protease regulatory subunit 7 (EHI_080890)
- 26S protease regulatory subunit 7 (UREG_01412)
- 26S protease regulatory subunit 7 (PITG_10169)
- proteasome 26S subunit, ATPase 2 (Psmc2)
- 26S protease regulatory subunit 7 (GL50803_86683)
- 26S protease regulatory subunit 7 (Tsp_09237)
- proteasome (prosome, macropain) 26S subunit, ATPase 2 (Psmc2)
- proteasome 26S subunit, ATPase 2 (psmc2)
- DDBDRAFT_0168337
- DDBDRAFT_0232966
- DDB_0168337
- DDB_0232966
- MSS1
- Nbla10058
- NCU02840.1
- psmc2
- S7
- xMSS1
- zgc:63995
Gene-IDs for different species
Protein level used designations for PSMC2
- 26S protease regulatory subunit 7
- 26S proteasome AAA-ATPase subunit RPT1
- proteasome 26S subunit ATPase 2
- 26S proteasome ATPase 2 subunit
- mammalian suppressor of sgv-1 of yeast
- protease 26S subunit 7
- proteasome 26S subunit, ATPase, 2
- putative protein product of Nbla10058
- proteasome (prosome, macropain) 26S subunit, ATPase 2
Proteomics products related to PSMC2 Gene
Other products related to PSMC2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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