PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11, PTPN11)
Short Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
More information related to gene PTPN11.
More information related to gene PTPN11.
Products related to PTPN11 Gene:
Recommended next Filters:
82 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- NCBI Accession:
- NM_013088
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- NCBI Accession:
- NM_011202
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- NCBI Accession:
- NM_002834
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- NCBI Accession:
- NM_013088
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- NCBI Accession:
- NM_002834
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- NCBI Accession:
- NM_011202
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
Synonyms and alternative names related to PTPN11
- protein tyrosine phosphatase, non-receptor type 11 (PTPN11)
- protein tyrosine phosphatase, non-receptor type 11 (Ptpn11)
- protein tyrosine phosphatase, non-receptor type 11 S homeolog (ptpn11.S)
- protein tyrosine phosphatase, non-receptor type 11, a (ptpn11a)
- protein tyrosine phosphatase, non-receptor type 11, b (ptpn11b)
- 2700084A17Rik
- AW536184
- BPTP3
- bptp3
- CFC
- cfc
- fa14b09
- NS1
- ns1
- PTP-1D
- ptp-2
- PTP1D
- PTP2C
- ptp2c
- ptpn11
- ptpn11-a
- ptpn11-b
- SAP-2
- SH-PTP2
- SH-PTP3
- SHP-2
- shp-2
- SHP2
- Shp2
- shp2
- Syp
- SYP
- wu:fa14b09
- wu:fi24f03
- zgc:55388
- zgc:63553
Gene-IDs for different species
Protein level used designations for PTPN11
- PTP-2C
- protein-tyrosine phosphatase 1D
- protein-tyrosine phosphatase 2C
- tyrosine-protein phosphatase non-receptor type 11
- SH2 domain-containing protein tyrosine phosphatase-2
- protein-tyrosine phosphatase SYP
- PTP-1D
- SH-PTP2 protein tyrosine phosphatase non-receptor type 11
- SH-PTP2 protein tyrosine phosphatase, non-receptor type 11
- SHP-2
- encodes catalytic domain
- protein tyrosine phosphatase SH-PTP2
- protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
- SH-PTP2
- cSH-PTP2
- non-receptor type protein tyrosine phosphatase SHP2
- phosphotyrosyl-protein phosphatase
- protein tyrosine phosphatase, non-receptor type 11 S homeolog
- LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 11
- protein-tyrosine phosphatase SHP-2a
- protein tyrosine phosphatase, non-receptor type 11, b
- protein-tyrosine phosphatase SHP-2b
- shp3 protein
Proteomics products related to PTPN11 Gene
Other products related to PTPN11 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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