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PTPN2 (Protein tyrosine Phosphatase, Non-Receptor Type 2, PTPN2)

Short Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011].
More information related to gene PTPN2.

Products related to PTPN2 Gene:

81 results :

Human PTPN2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5757004
Datasheet
Catalog No. ABIN5757004
Type:
ORF
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Insert length:
1164 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PTPN2 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5757003
Datasheet
Catalog No. ABIN5757003
Type:
ORF
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Insert length:
1062 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human PTPN2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4479985
Datasheet
Catalog No. ABIN4479985
Type:
cDNA
Application:
Protein Expression
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Insert length:
1062 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PTPN2 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4479984
Datasheet
Catalog No. ABIN4479984
Type:
cDNA
Application:
Protein Expression
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Insert length:
1062 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse PTPN2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
NCBI Accession:
NM_008977
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150873
Datasheet
Catalog No. ABIN5150873
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
NCBI Accession:
NM_008977
Species:
Mouse
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptpn2
Format:
Viral Particles
Storage:
-80 °C
Human PTPN2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
NCBI Accession:
NM_080422
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150871
Datasheet
Catalog No. ABIN5150871
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
NCBI Accession:
NM_080422
Species:
Human
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PTPN2
Format:
Viral Particles
Storage:
-80 °C
Rat PTPN2 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
NCBI Accession:
NM_053990
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5150875
Datasheet
Catalog No. ABIN5150875
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
NCBI Accession:
NM_053990
Species:
Rat
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptpn2
Format:
Viral Particles
Storage:
-80 °C
Human PTPN2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4838448
Datasheet
Catalog No. ABIN4838448
Type:
cDNA
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Insert length:
1164 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PTPN2 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4838449
Datasheet
Catalog No. ABIN4838449
Type:
cDNA
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Insert length:
1062 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human PTPN2 cDNA Clone in Bacterial Expression Vector (His-MBP)
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4709319
Datasheet
Catalog No. ABIN4709319
Type:
cDNA
Application:
Cloning
Gene:
Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2)
Species:
Human
Synonyms:
PTPN2, Ptpn2, ptpn2.S, ptpn2b, ptpn2a, ptpn2.L
Insert length:
1062 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Cloning (Clon)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pRS
    • pCas-Guide
    • pDONR223
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRFP-C-RS
    • pCMV6-XL4
    • pCMV6-XL5
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PTPN2

  • protein tyrosine phosphatase, non-receptor type 2 (PTPN2)
  • protein tyrosine phosphatase, non-receptor type 2 (Ptpn2)
  • protein tyrosine phosphatase, non-receptor type 2 S homeolog (ptpn2.S)
  • protein tyrosine phosphatase, non-receptor type 2, b (ptpn2b)
  • protein tyrosine phosphatase, non-receptor type 2, a (ptpn2a)
  • protein tyrosine phosphatase, non-receptor type 2 L homeolog (ptpn2.L)
  • AI325124
  • cb806
  • hm:zeh1546
  • PTN2
  • ptn2
  • PTP-1B
  • ptpn2
  • ptpn2l
  • PTPT
  • Ptpt
  • ptpt
  • TC-PTP
  • tc-ptp
  • TCELLPTP
  • tcellptp
  • TCPTP
  • tcptp
  • wu:fc10h07
  • zgc:55339
  • zgc:63623
  • zgc:76973

Gene-IDs for different species

Protein level used designations for PTPN2

  • T-cell protein tyrosine phosphatase
  • tyrosine-protein phosphatase non-receptor type 2
  • MPTP
  • T cell protein-tyrosine phosphatase
  • protein-tyrosine phosphatase PTP-2
  • protein-tyrosine phosphatase PTP-S
  • phosphoprotein phosphatase
  • protein tyrosine phosphatase 1B
  • protein tyrosine phosphatase, non-receptor type 2, like
  • protein tyrosine phosphatase, non-receptor type 2, a
  • protein tyrosine phosphatase, non-receptor type 2 L homeolog
Other products related to PTPN2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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