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PTRF (Polymerase I and Transcript Release Factor, PTRF)

Short Description: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009].
More information related to gene PTRF.

Products related to PTRF Gene:

53 results

OriGene rc209277 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232,NP_036364
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5360820
$452.43
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Gene ID:
284119 (Human, PTRF)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4936141
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
OriGene sr317108 RNAi PTRF Species: Human HPLC purified
Application:
RNA Interference
Gene:
Polymerase I and Transcript Release Factor
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3314104
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL6
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • gRNA + Cas9
    • ORF
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PTRF

  • caveolae associated protein 1 L homeolog (cavin1.L)
  • polymerase I and transcript release factor (PTRF)
  • caveolae associated protein 1 (cavin1)
  • caveolae associated protein 1 (CAVIN1)
  • caveolae associated protein 1b (cavin1b)
  • caveolae associated 1 (Cavin1)
  • caveolae associated protein 1 (Cavin1)
  • 2310075E07Rik
  • AW546441
  • Cav-p60
  • CAVIN
  • Cavin
  • cavin-1
  • CAVIN1
  • CGL4
  • fd20g07
  • MGC53017
  • MGC89141
  • PTRF
  • ptrf
  • wu:fd20g07
  • zgc:162917

Gene-IDs for different species

Protein level used designations for PTRF

  • polymerase I and transcript release factor
  • leucine zipper protein
  • leucine-zipper protein
  • polymerase I and transcript release factor-like
  • RNA polymerase I and transcript release factor
  • TTF-I interacting peptide 12
  • cavin-1
  • cav-p60
  • cavin
Other products related to PTRF such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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