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PTRF (Polymerase I and Transcript Release Factor, PTRF)

Short Description: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009].
More information related to gene PTRF.

Products related to PTRF Gene:

53 results :

Human PTRF ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5728005
Datasheet
Catalog No. ABIN5728005
Type:
ORF
Application:
Cloning
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Species:
Human
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Insert length:
1173 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PTRF CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_001105841
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5095382
Datasheet
Catalog No. ABIN5095382
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_001105841
Species:
Rat
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptrf
Format:
Viral Particles
Storage:
-80 °C
Mouse PTRF CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_008986
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5095380
Datasheet
Catalog No. ABIN5095380
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_008986
Species:
Mouse
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptrf
Format:
Viral Particles
Storage:
-80 °C
Human PTRF CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5095378
Datasheet
Catalog No. ABIN5095378
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Species:
Human
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PTRF
Format:
Viral Particles
Storage:
-80 °C
Mouse PTRF ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_008986
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5728006
Datasheet
Catalog No. ABIN5728006
Type:
ORF
Application:
Cloning
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_008986
Species:
Mouse
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Insert length:
1179 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PTRF ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_001105841
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5728007
Datasheet
Catalog No. ABIN5728007
Type:
ORF
Application:
Cloning
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_001105841
Species:
Rat
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Insert length:
1179 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Rat PTRF CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_001105841
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5210606
Datasheet
Catalog No. ABIN5210606
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_001105841
Species:
Rat
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptrf
Format:
Viral Particles
Storage:
-80 °C
Mouse PTRF CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_008986
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5210604
Datasheet
Catalog No. ABIN5210604
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_008986
Species:
Mouse
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Ptrf
Format:
Viral Particles
Storage:
-80 °C
Human PTRF CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5210602
Datasheet
Catalog No. ABIN5210602
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Species:
Human
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of PTRF
Format:
Viral Particles
Storage:
-80 °C
Human PTRF cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4489958
Datasheet
Catalog No. ABIN4489958
Type:
cDNA
Application:
Protein Expression
Gene:
Polymerase I and Transcript Release Factor (PTRF)
NCBI Accession:
NM_012232
Species:
Human
Synonyms:
cavin1.L, PTRF, cavin1, CAVIN1, cavin1b, Cavin1
Insert length:
903 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pRFP-C-RS
    • pCMV6-AC-GFP
    • pCMV6-XL6
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • gRNA + Cas9
    • ORF
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
    • SP6 Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to PTRF

  • caveolae associated protein 1 L homeolog (cavin1.L)
  • polymerase I and transcript release factor (PTRF)
  • caveolae associated protein 1 (cavin1)
  • caveolae associated protein 1 (CAVIN1)
  • caveolae associated protein 1b (cavin1b)
  • caveolae associated 1 (Cavin1)
  • caveolae associated protein 1 (Cavin1)
  • 2310075E07Rik
  • AW546441
  • Cav-p60
  • CAVIN
  • Cavin
  • cavin-1
  • CAVIN1
  • CGL4
  • fd20g07
  • MGC53017
  • MGC89141
  • PTRF
  • ptrf
  • wu:fd20g07
  • zgc:162917

Gene-IDs for different species

Protein level used designations for PTRF

  • polymerase I and transcript release factor
  • leucine zipper protein
  • leucine-zipper protein
  • polymerase I and transcript release factor-like
  • RNA polymerase I and transcript release factor
  • TTF-I interacting peptide 12
  • cavin-1
  • cav-p60
  • cavin
Other products related to PTRF such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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