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RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1, RAF1)

Short Description: This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].
More information related to gene RAF1.

Products related to RAF1 Gene:

65 results

gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
NCBI Accession:
NM_002880
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5114947
$1,511.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
NCBI Accession:
NM_029780
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230297
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
NCBI Accession:
NM_012639
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230299
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
NCBI Accession:
NM_002880
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5230293
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
Gene ID:
5894 (Human, RAF1)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5317934
$235.38
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 19 Business Days
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
NCBI Accession:
NM_002880
Gene ID:
5894 (Human, RAF1)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4936042
$379.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
OriGene rg201983 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
NCBI Accession:
NM_002880,NP_002871
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5394497
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
OriGene sr418654 RNAi RAF1 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3266175
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr500278 RNAi RAF1 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3350779
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr303972 RNAi RAF1 Species: Human HPLC purified
Pubmed 1
Application:
RNA Interference
Gene:
V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3343745
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCMV6-XL5
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-AC-GFP
    • pCMV6-XL4
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to RAF1

  • Raf-1 proto-oncogene, serine/threonine kinase (RAF1)
  • Raf-1 proto-oncogene, serine/threonine kinase (Raf1)
  • Raf-1 proto-oncogene, serine/threonine kinase a (raf1a)
  • Raf-1 proto-oncogene, serine/threonine kinase (raf1)
  • v-raf-leukemia viral oncogene 1 (Raf1)
  • Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S)
  • 6430402F14Rik
  • AA990557
  • BB129353
  • c-Raf
  • c-raf
  • CRAF
  • craf
  • cRaf
  • Craf1
  • D830050J10Rik
  • NS5
  • raf
  • Raf-1
  • raf1
  • RAF1
  • v-Raf

Gene-IDs for different species

Protein level used designations for RAF1

  • Oncogene RAF1
  • RAF proto-oncogene serine/threonine-protein kinase
  • proto-oncogene c-RAF
  • raf proto-oncogene serine/threonine protein kinase
  • C-RAF
  • cRaf
  • murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV)
  • raf-1
  • v-raf-1 murine leukemia viral oncogene homolog 1
  • murine leukemia viral oncogene homolog
  • serine/threonine protein kinase RAF1
  • MIL proto-oncogene serine/threonine-protein kinase
  • RAF-1
  • c-mil protein
  • murine leukemia viral (v-raf-1) oncogene homolog 1
  • RAF proto-oncogene serine/threonine-protein kinase-like
  • Craf1 transforming
  • murine sarcoma 3611 oncogene 1
  • sarcoma 3611 oncogene
  • v-raf-1 leukemia viral oncogene 1
  • Proto-oncogene c-RAF
  • Raf-1
Other products related to RAF1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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