SETD8 (SET Domain Containing (Lysine Methyltransferase) 8, SETD8)
Short Description: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).
More information related to gene SETD8.
More information related to gene SETD8.
Products related to SETD8 Gene:
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47 results
OriGene sc113114
cDNA
PExp
Mammalian Expression Vector
pCMV6-XL6
Ampicillin
Enhanced CMV Promoter
unconjugated
Transient
1
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- NCBI Accession:
- NM_020382,NP_065115
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-XL6
- Resistance Gene:
- Ampicillin
- Promoter:
- Enhanced CMV Promoter, SP6 Promoter
- Expression:
- Transient
Catalog No. ABIN3393781
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene rr216360
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5455918
$326.70
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene rc208219l1
ORF
PExp
Lentiviral Vector
pLenti-C-Myc-DDK
Chloramphenicol
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- NCBI Accession:
- NM_020382,NP_065115
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-Myc-DDK
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5455920
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rc208219l2
ORF
PExp
Lentiviral Vector
pLenti-C-mGFP
Chloramphenicol
CMV Promoter
GFP tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- NCBI Accession:
- NM_020382,NP_065115
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-C-mGFP
- Resistance Gene:
- Chloramphenicol
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient
Catalog No. ABIN5455919
$749.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc208219
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- NCBI Accession:
- NM_020382,NP_065115
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5455917
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rg208219
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5455916
$484.11
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene sr317948
RNAi
SETD8
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3314941
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to SETD8
- lysine methyltransferase 5A (KMT5A)
- lysine methyltransferase 5A (Kmt5a)
- lysine methyltransferase 5Ab (kmt5ab)
- lysine methyltransferase 5A S homeolog (kmt5a.S)
- lysine methyltransferase 5Aa (kmt5aa)
- 2410195B05Rik
- AA617402
- AW536475
- KMT5A
- kmt5a
- kmt5a-a
- PR-Set7
- PR-SET7
- Pr-set7
- RGD1305893
- SET07
- SET8
- set8a
- Setd8
- setd8
- setd8-a
- setd8a
- setd8b
- wu:fc23f12
- wu:fj33f02
- zgc:153719
- zgc:171649
Gene-IDs for different species
Protein level used designations for SETD8
- H4-K20-HMTase SETD8
- H4-K20-specific histone methyltransferase
- H4K20-specific histone methyltransferase splice variant Set8b
- N-lysine methyltransferase SETD8
- PR/SET domain containing protein 8
- PR/SET domain-containing protein 07
- PR/SET07
- SET domain-containing protein 8
- histone-lysine N-methyltransferase SETD8
- lysine N-methyltransferase 5A
- PR-Set7
- SET domain-containing 8
- SET domain containing (lysine methyltransferase) 8b
- SET domain containing 8b
- N-lysine methyltransferase KMT5A
- SET domain containing (lysine methyltransferase) 8
- histone methyltransferase Pr-set7/Set8
- lysine (K)-specific methyltransferase 5A
- Histone-lysine N-methyltransferase KMT5A-A
- Lysine-specific methylase 5A-A
- N-lysine methyltransferase KMT5A-A
- N-lysine methyltransferase SETD8-A
- SET domain-containing protein 8-A
- histone-lysine N-methyltransferase KMT5A-A
- histone-lysine N-methyltransferase SETD8-A
- lysine (K)-specific methyltransferase 5A S homeolog
- lysine-specific methylase 5A-A
- PR/SET domain containing protein 8a
- SET domain containing (lysine methyltransferase) 8a
Proteomics products related to SETD8 Gene
Other products related to SETD8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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