SETD8 (SET Domain Containing (Lysine Methyltransferase) 8, SETD8)
Short Description: Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).
More information related to gene SETD8.
More information related to gene SETD8.
Products related to SETD8 Gene:
Recommended next Filters:
47 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- NCBI Accession:
- NM_030241
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- NCBI Accession:
- NM_020382
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- NCBI Accession:
- NM_030241
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- SET Domain Containing (Lysine Methyltransferase) 8 (SETD8)
- NCBI Accession:
- NM_001246665
- Species:
- Rat
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
Synonyms and alternative names related to SETD8
- lysine methyltransferase 5A (KMT5A)
- lysine methyltransferase 5A (Kmt5a)
- lysine methyltransferase 5Ab (kmt5ab)
- lysine methyltransferase 5A S homeolog (kmt5a.S)
- lysine methyltransferase 5Aa (kmt5aa)
- 2410195B05Rik
- AA617402
- AW536475
- KMT5A
- kmt5a
- kmt5a-a
- PR-Set7
- PR-SET7
- Pr-set7
- RGD1305893
- SET07
- SET8
- set8a
- Setd8
- setd8
- setd8-a
- setd8a
- setd8b
- wu:fc23f12
- wu:fj33f02
- zgc:153719
- zgc:171649
Gene-IDs for different species
Protein level used designations for SETD8
- H4-K20-HMTase SETD8
- H4-K20-specific histone methyltransferase
- H4K20-specific histone methyltransferase splice variant Set8b
- N-lysine methyltransferase SETD8
- PR/SET domain containing protein 8
- PR/SET domain-containing protein 07
- PR/SET07
- SET domain-containing protein 8
- histone-lysine N-methyltransferase SETD8
- lysine N-methyltransferase 5A
- PR-Set7
- SET domain-containing 8
- SET domain containing (lysine methyltransferase) 8b
- SET domain containing 8b
- N-lysine methyltransferase KMT5A
- SET domain containing (lysine methyltransferase) 8
- histone methyltransferase Pr-set7/Set8
- lysine (K)-specific methyltransferase 5A
- Histone-lysine N-methyltransferase KMT5A-A
- Lysine-specific methylase 5A-A
- N-lysine methyltransferase KMT5A-A
- N-lysine methyltransferase SETD8-A
- SET domain-containing protein 8-A
- histone-lysine N-methyltransferase KMT5A-A
- histone-lysine N-methyltransferase SETD8-A
- lysine (K)-specific methyltransferase 5A S homeolog
- lysine-specific methylase 5A-A
- PR/SET domain containing protein 8a
- SET domain containing (lysine methyltransferase) 8a
Proteomics products related to SETD8 Gene
Other products related to SETD8 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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