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SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3, SHANK3)

Short Description: This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012].
More information related to gene SHANK3.

Products related to SHANK3 Gene:

48 results

OriGene sr423164 RNAi SHANK3 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3350012
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sr501650 RNAi SHANK3 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3351955
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene rn201936 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021676,NP_067708
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3376057
$1,592.91
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene mc224879 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021423,NP_067398
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3376056
$1,584.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene rc235332 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_033517,NP_277052
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5364655
$2,303.73
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 71 to 72 Business Days
OriGene rr201936 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5364656
$1,591.92
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 6 to 9 Business Days
OriGene rg235332 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5364654
$2,501.73
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 71 to 72 Business Days
OriGene sr313832 RNAi SHANK3 Species: Human HPLC purified
Application:
RNA Interference
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3
Species:
Human
Purification:
HPLC purified
Catalog No. ABIN3310836
$435.60
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 4 to 9 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pORF
    • pCMV6-AC-GFP
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
    • ORF
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SHANK3

  • SH3 and multiple ankyrin repeat domains 3 (SHANK3)
  • SH3 and multiple ankyrin repeat domains protein 3 (shank3)
  • SH3 and multiple ankyrin repeat domains 3 (Shank3)
  • AI841104
  • DEL22q13.3
  • PROSAP2
  • Prosap2
  • PSAP2
  • SCZD15
  • Shank3b
  • SPANK-2

Gene-IDs for different species

Protein level used designations for SHANK3

  • SH3 and multiple ankyrin repeat domains 3
  • SH3 and multiple ankyrin repeat domains protein 3-like
  • SH3 and multiple ankyrin repeat domains protein 3
  • proline rich synapse associated protein 2
  • shank postsynaptic density protein
  • SH3/ankyrin domain gene 3
  • SPANK-2
  • Shank postsynaptic density protein 3a
  • proline-rich synapse-associated protein 2
  • SH3 and multiple ankyrin repeat domains-like protein 3 variant 1
  • SH3 and multiple ankyrin repeat domains-like protein 3 variant 2
  • SH3 and multiple ankyrin repeat domains-like protein 3 variant 3
  • SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1
  • proSAP2
Other products related to SHANK3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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