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SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3, SHANK3)

Short Description: This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012].
More information related to gene SHANK3.

Products related to SHANK3 Gene:

48 results

ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021423
Species:
Mouse
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5729204
$2,651.25
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021676
Species:
Rat
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5729205
$3,526.25
Plus shipping costs $50.00
1 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_001080420
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212932
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_001080420
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212931
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021423
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212934
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021423
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212933
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021676
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212936
$857.21
Plus shipping costs $50.00, if applicable $20.00 dry ice
300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021676
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5212935
$1,968.75
Plus shipping costs $50.00, if applicable $20.00 dry ice
3 x 300 μL
Shipping to: United States
Delivery in 31 to 42 Business Days
cDNA Clon Bacterial Expression Vector pPB-His-MBP Kanamycin T7 Promoter His-MBP Transient
Type:
cDNA
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_021676
Species:
Rat
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient
Catalog No. ABIN4754569
$5,927.06
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)
NCBI Accession:
NM_001080420
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4840020
$4,576.40
Plus shipping costs $50.00
500 ng
Shipping to: United States
Delivery in 21 to 32 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • RNA Interference (RNAi)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCas-Guide
    • pORF
    • pCMV6-AC-GFP
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
  • Insert
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
    • ORF
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SHANK3

  • SH3 and multiple ankyrin repeat domains 3 (SHANK3)
  • SH3 and multiple ankyrin repeat domains protein 3 (shank3)
  • SH3 and multiple ankyrin repeat domains 3 (Shank3)
  • AI841104
  • DEL22q13.3
  • PROSAP2
  • Prosap2
  • PSAP2
  • SCZD15
  • Shank3b
  • SPANK-2

Gene-IDs for different species

Protein level used designations for SHANK3

  • SH3 and multiple ankyrin repeat domains 3
  • SH3 and multiple ankyrin repeat domains protein 3-like
  • SH3 and multiple ankyrin repeat domains protein 3
  • proline rich synapse associated protein 2
  • shank postsynaptic density protein
  • SH3/ankyrin domain gene 3
  • SPANK-2
  • Shank postsynaptic density protein 3a
  • proline-rich synapse-associated protein 2
  • SH3 and multiple ankyrin repeat domains-like protein 3 variant 1
  • SH3 and multiple ankyrin repeat domains-like protein 3 variant 2
  • SH3 and multiple ankyrin repeat domains-like protein 3 variant 3
  • SH3 and multiple ankyrin repeat domains-like protein 3 variant d-1
  • proSAP2
Other products related to SHANK3 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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