SLC46A1 (Solute Carrier Family 46 (Folate Transporter), Member 1, SLC46A1)
Short Description: This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia, hypoimmunoglobulinemia, and recurrent infections. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011].
More information related to gene SLC46A1.
More information related to gene SLC46A1.
Products related to SLC46A1 Gene:
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55 results
OriGene rc232708
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
- NCBI Accession:
- NM_001242366,NP_001229295
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5437976
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rg214417
ORF
PExp
Mammalian Expression Vector
pCMV6-AC-GFP
Ampicillin
CMV Promoter
GFP tag
Stable
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-AC-GFP
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Stable, Transient
Catalog No. ABIN5437973
$650.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene rc214417
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
- NCBI Accession:
- NM_080669,NP_542400
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5437975
$452.43
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 8 to 11 Business Days
OriGene rr212206
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
- NCBI Accession:
- NM_001013969,NP_001013991
- Species:
- Rat
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5437977
$497.97
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 21 to 22 Business Days
OriGene sr314375
RNAi
SLC46A1
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Solute Carrier Family 46 (Folate Transporter), Member 1
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3311377
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to SLC46A1
- solute carrier family 46 member 1 (SLC46A1)
- solute carrier family 46 (folate transporter), member 1 (slc46a1)
- solute carrier family 46 member 1 (Slc46a1)
- solute carrier family 46, member 1 (Slc46a1)
- 1110002C08Rik
- D11Ertd18e
- G21
- HCP1
- PCFT
- Pcft
- RGD1309472
- TRPE
Gene-IDs for different species
Protein level used designations for SLC46A1
- solute carrier family 46, member 1
- solute carrier family 46 (folate transporter), member 1
- proton-coupled folate transporter-like
- heme carrier protein 1
- proton-coupled folate transporter
- PCFT/HCP1
- retinal pigment epithelilum transporter
- retinal pigment epithelium transporter
- solute carrier family 46 member 1
Proteomics products related to SLC46A1 Gene
Other products related to SLC46A1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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