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SLC46A1 (Solute Carrier Family 46 (Folate Transporter), Member 1, SLC46A1)

Short Description: This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes, optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a heme transporter in duodenal enterocytes, and potentially in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene are associated with autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia, hypoimmunoglobulinemia, and recurrent infections. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011].
More information related to gene SLC46A1.

Products related to SLC46A1 Gene:

55 results :

Human SLC46A1 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5751652
Datasheet
Catalog No. ABIN5751652
Type:
ORF
Application:
Cloning
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
Species:
Human
Synonyms:
SLC46A1, slc46a1, Slc46a1
Insert length:
1296 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human SLC46A1 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4481316
Datasheet
Catalog No. ABIN4481316
Type:
cDNA
Application:
Protein Expression
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
Species:
Human
Synonyms:
SLC46A1, slc46a1, Slc46a1
Insert length:
1296 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse SLC46A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_026740
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255769
Datasheet
Catalog No. ABIN5255769
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_026740
Species:
Mouse
Synonyms:
SLC46A1, slc46a1, Slc46a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc46a1
Format:
Viral Particles
Storage:
-80 °C
Rat SLC46A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_001013969
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255771
Datasheet
Catalog No. ABIN5255771
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_001013969
Species:
Rat
Synonyms:
SLC46A1, slc46a1, Slc46a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc46a1
Format:
Viral Particles
Storage:
-80 °C
Human SLC46A1 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_080669
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5255767
Datasheet
Catalog No. ABIN5255767
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_080669
Species:
Human
Synonyms:
SLC46A1, slc46a1, Slc46a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SLC46A1
Format:
Viral Particles
Storage:
-80 °C
Mouse SLC46A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_026740
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140272
Datasheet
Catalog No. ABIN5140272
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_026740
Species:
Mouse
Synonyms:
SLC46A1, slc46a1, Slc46a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc46a1
Format:
Viral Particles
Storage:
-80 °C
Rat SLC46A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_001013969
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140274
Datasheet
Catalog No. ABIN5140274
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_001013969
Species:
Rat
Synonyms:
SLC46A1, slc46a1, Slc46a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Slc46a1
Format:
Viral Particles
Storage:
-80 °C
Human SLC46A1 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_080669
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5140270
Datasheet
Catalog No. ABIN5140270
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
NCBI Accession:
NM_080669
Species:
Human
Synonyms:
SLC46A1, slc46a1, Slc46a1
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of SLC46A1
Format:
Viral Particles
Storage:
-80 °C
Human SLC46A1 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4840411
Datasheet
Catalog No. ABIN4840411
Type:
cDNA
Application:
Cloning
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
Species:
Human
Synonyms:
SLC46A1, slc46a1, Slc46a1
Insert length:
1296 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human SLC46A1 cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4624787
Datasheet
Catalog No. ABIN4624787
Type:
cDNA
Application:
Cloning
Gene:
Solute Carrier Family 46 (Folate Transporter), Member 1 (SLC46A1)
Species:
Human
Synonyms:
SLC46A1, slc46a1, Slc46a1
Insert length:
1296 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • DYKDDDDK Tag
    • RFP tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pCMV6-AC-GFP
    • pCas-Guide
    • pRFP-C-RS
    • pcDNA3.1+C-(K)-DYK
    • pDONR223
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SLC46A1

  • solute carrier family 46 member 1 (SLC46A1)
  • solute carrier family 46 (folate transporter), member 1 (slc46a1)
  • solute carrier family 46 member 1 (Slc46a1)
  • solute carrier family 46, member 1 (Slc46a1)
  • 1110002C08Rik
  • D11Ertd18e
  • G21
  • HCP1
  • PCFT
  • Pcft
  • RGD1309472
  • TRPE

Gene-IDs for different species

Protein level used designations for SLC46A1

  • solute carrier family 46, member 1
  • solute carrier family 46 (folate transporter), member 1
  • proton-coupled folate transporter-like
  • heme carrier protein 1
  • proton-coupled folate transporter
  • PCFT/HCP1
  • retinal pigment epithelilum transporter
  • retinal pigment epithelium transporter
  • solute carrier family 46 member 1
Other products related to SLC46A1 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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