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SUPT5H (Transcription Elongation Factor SPT5, SUPT5H)

Short Description: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV- 1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.
More information related to gene SUPT5H.

Products related to SUPT5H Gene:

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55 results

Human SUPT5H ORF Clone in Lenti Particles (GFP tag)
OriGene rc226318l2v ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN6428397
$1,478.07
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 21 to 27 Business Days
Details
Details
Human SUPT5H ORF Clone in Lenti Particles (Myc-DYKDDDDK Tag)
OriGene rc226318l1v ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN6428396
$1,478.07
Plus shipping costs $50.00, if applicable $20.00 dry ice
200 μL
Shipping to: United States
Delivery in 21 to 27 Business Days
Details
Details
Human SUPT5H ORF Clone in Gateway Cloning Vector
ORF Clon Gateway Cloning Vector pDONR223 Spectinomycin unconjugated
Type:
ORF
Application:
Cloning
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Gene ID:
6829 (Human, SUPT5H)
Vector type:
Gateway Cloning Vector
Vector backbone:
pDONR223
Resistance Gene:
Spectinomycin
Catalog No. ABIN5322868
$258.54
Plus shipping costs $50.00
2 μg
Shipping to: United States
Delivery in 15 to 19 Business Days
Details
Details
Human SUPT5H shRNA in Lentiviral Vector (GFP tag)
OriGene tl309005 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3754212
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human SUPT5H shRNA in Retroviral Vector (GFP tag)
OriGene tg309005 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Pubmed 1
Type:
shRNA
Application:
RNA Interference
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3733874
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse SUPT5H shRNA in Lentiviral Vector (GFP tag)
OriGene tl502180 shRNA RNAi Lentiviral Vector pGFP-C-shLenti Chloramphenicol U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pGFP-C-shLenti
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3703921
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse SUPT5H shRNA in Retroviral Vector (GFP tag)
OriGene tg502180 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3684219
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human SUPT5H shRNA in Retroviral Vector
OriGene tr309005 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Pubmed 1
Type:
shRNA
Application:
RNA Interference
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Human
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3650971
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Rat SUPT5H shRNA in Retroviral Vector (RFP tag)
OriGene tf706053 shRNA RNAi Retroviral Vector pRFP-C-RS Chloramphenicol U6 Promoter RFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable
Catalog No. ABIN3486343
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Mouse SUPT5H shRNA in Retroviral Vector
OriGene tr502180 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Transcription Elongation Factor SPT5 (SUPT5H)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3534522
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Cited in publications
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Cloning (Clon)
    • Genome Editing with Engineered Nucleases (GEEN)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pCMV6-AC-GFP
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pRS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pcDNA3.1+C-(K)-DYK
    • pCMV6-XL5
    • pCas-Guide
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Retroviral Vector
    • Bacterial Expression Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • ORF
    • cDNA
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • CMV Promoter
    • U6 Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to SUPT5H

  • SPT5 homolog, DSIF elongation factor subunit (SUPT5H)
  • transcription elongation factor SPT5 (LOC413814)
  • Transcription elongation factor Spt5 (AT2G34210)
  • transcription elongation factor Spt5 (spt5)
  • transcription elongation factor spt5 (MGYG_08422)
  • transcription elongation factor spt5 (TERG_05483)
  • hypothetical protein (PGTG_18458)
  • SPT5 homolog, DSIF elongation factor subunit (supt5h)
  • SPT5 homolog, DSIF elongation factor subunit (Supt5h)
  • SPT5 homolog, DSIF elongation factor subunit S homeolog (supt5h.S)
  • CG7626 gene product from transcript CG7626-RA (Spt5)
  • Transcription elongation factor SPT5 (spt-5)
  • transcription elongation factor (SPT5)
  • CaO19.1453
  • CG7626
  • dDSIF
  • Dmel\\CG7626
  • DSIF
  • Dspt5
  • dSpt5
  • etID10129.15
  • etID37101.15
  • F13P17.5
  • F13P17_5
  • fb37g01
  • fb95e05
  • fog
  • foggy
  • SPT5
  • Spt5
  • spt5
  • SPT5H
  • spt5h
  • Tat-CT1
  • tat-ct1
  • wu:fb37g01
  • wu:fb95e05
  • wu:fc10f02

Gene-IDs for different species

Protein level used designations for SUPT5H

  • DRB sensitivity-inducing factor 160 kDa subunit
  • DRB sensitivity-inducing factor large subunit
  • DSIF large subunit
  • DSIF p160
  • Tat-cotransactivator 1 protein
  • hSPT5
  • transcription elongation factor SPT5
  • transcription elongation factor Spt5
  • transcription elongation factor spt5
  • protein foggy
  • transcription elongation regulator foggy
  • CG7626-PA
  • Spt5-PA
  • Chromatin elongation factor SPT5
Other products related to SUPT5H such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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