SUPT5H (Transcription Elongation Factor SPT5, SUPT5H)
Short Description: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV- 1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.
More information related to gene SUPT5H.
More information related to gene SUPT5H.
Products related to SUPT5H Gene:
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55 results
OriGene rc226321
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- NCBI Accession:
- NM_001111020,NP_001104490
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5345521
$1,030.59
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
OriGene rc226322
ORF
PExp
Mammalian Expression Vector
pCMV6-Entry
Kanamycin
CMV Promoter
Myc-DYKDDDDK Tag
Transient
1
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- NCBI Accession:
- NM_001130824,NP_001124296
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pCMV6-Entry
- Resistance Gene:
- Kanamycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- Myc-DYKDDDDK Tag
- Expression:
- Transient
Catalog No. ABIN5345522
$1,030.59
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 41 to 42 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- NCBI Accession:
- NM_001130825
- Gene ID:
- 6829 (Human, SUPT5H)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4945152
$799.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 2 to 5 Business Days
ORF
PExp
Mammalian Expression Vector
pcDNA3.1+C-(K)-DYK
Ampicillin
CMV Promoter
DYKDDDDK Tag
Transient
- Type:
- ORF
- Application:
- Protein Expression
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- NCBI Accession:
- NM_001130824
- Gene ID:
- 6829 (Human, SUPT5H)
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pcDNA3.1+C-(K)-DYK
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- DYKDDDDK Tag
- Expression:
- Transient, Stable
Catalog No. ABIN4934837
$549.00
Plus shipping costs $50.00
10 μg
Shipping to:
United States
Delivery in 4 to 7 Business Days
OriGene sr304660
RNAi
SUPT5H
Species: Human
HPLC purified
- Application:
- RNA Interference
- Gene:
- Transcription Elongation Factor SPT5
- Species:
- Human
- Purification:
- HPLC purified
Catalog No. ABIN3344432
$512.82
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to SUPT5H
- SPT5 homolog, DSIF elongation factor subunit (SUPT5H)
- transcription elongation factor SPT5 (LOC413814)
- Transcription elongation factor Spt5 (AT2G34210)
- transcription elongation factor Spt5 (spt5)
- transcription elongation factor spt5 (MGYG_08422)
- transcription elongation factor spt5 (TERG_05483)
- hypothetical protein (PGTG_18458)
- SPT5 homolog, DSIF elongation factor subunit (supt5h)
- SPT5 homolog, DSIF elongation factor subunit (Supt5h)
- SPT5 homolog, DSIF elongation factor subunit S homeolog (supt5h.S)
- CG7626 gene product from transcript CG7626-RA (Spt5)
- Transcription elongation factor SPT5 (spt-5)
- transcription elongation factor (SPT5)
- CaO19.1453
- CG7626
- dDSIF
- Dmel\\CG7626
- DSIF
- Dspt5
- dSpt5
- etID10129.15
- etID37101.15
- F13P17.5
- F13P17_5
- fb37g01
- fb95e05
- fog
- foggy
- SPT5
- Spt5
- spt5
- SPT5H
- spt5h
- Tat-CT1
- tat-ct1
- wu:fb37g01
- wu:fb95e05
- wu:fc10f02
Gene-IDs for different species
Protein level used designations for SUPT5H
- DRB sensitivity-inducing factor 160 kDa subunit
- DRB sensitivity-inducing factor large subunit
- DSIF large subunit
- DSIF p160
- Tat-cotransactivator 1 protein
- hSPT5
- transcription elongation factor SPT5
- transcription elongation factor Spt5
- transcription elongation factor spt5
- protein foggy
- transcription elongation regulator foggy
- CG7626-PA
- Spt5-PA
- Chromatin elongation factor SPT5
Proteomics products related to SUPT5H Gene
Other products related to SUPT5H such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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