SUPT5H (Transcription Elongation Factor SPT5, SUPT5H)
Short Description: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A. DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter. Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II. TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme. Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites. DSIF can also positively regulate transcriptional elongation and is required for the efficient activation of transcriptional elongation by the HIV- 1 nuclear transcriptional activator, Tat. DSIF acts to suppress transcriptional pausing in transcripts derived from the HIV-1 LTR and blocks premature release of HIV-1 transcripts at terminator sequences.
More information related to gene SUPT5H.
More information related to gene SUPT5H.
Products related to SUPT5H Gene:
Recommended next Filters:
55 results :
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- Species:
- Human
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-HA
Kanamycin
CMV Promoter
HA tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-HA
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- HA tag
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- NCBI Accession:
- NM_013676
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
gRNA
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-PGK-Neo
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- NCBI Accession:
- NM_003169
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-PGK-Neo
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Neomycin
- Promoter:
- U6 Promoter, PGK Promoter
- Expression:
- Stable, Transient
ORF
Clon
Cloning Vector
pORF
Spectinomycin
unconjugated
Transient
- Type:
- ORF
- Application:
- Cloning
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- NCBI Accession:
- NM_013676
- Species:
- Mouse
- Vector type:
- Cloning Vector
- Vector backbone:
- pORF
- Resistance Gene:
- Spectinomycin
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-GST
Kanamycin
T7 Promoter
His-GST
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-GST
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-GST
- Expression:
- Transient
cDNA
Clon
Bacterial Expression Vector
pPB-N-His
Kanamycin
T7 Promoter
His tag
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-N-His
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His tag
- Expression:
- Transient
cDNA
PExp
Mammalian Expression Vector
pPM-C-His
Kanamycin
CMV Promoter
His tag
Stable
- Type:
- cDNA
- Application:
- Protein Expression
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- Species:
- Human
- Vector type:
- Mammalian Expression Vector
- Vector backbone:
- pPM-C-His
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Neomycin
- Promoter:
- CMV Promoter
- Fusion Tag:
- His tag
- Expression:
- Stable, Transient
cDNA
Clon
Bacterial Expression Vector
pPB-His-MBP
Kanamycin
T7 Promoter
His-MBP
Transient
- Type:
- cDNA
- Application:
- Cloning
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- Species:
- Human
- Vector type:
- Bacterial Expression Vector
- Vector backbone:
- pPB-His-MBP
- Resistance Gene:
- Kanamycin
- Promoter:
- T7 Promoter
- Fusion Tag:
- His-MBP
- Expression:
- Transient
gRNA + Cas9
PExp, GEEN
Lentiviral Vector
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Ampicillin
U6 Promoter
unconjugated
Stable
- Type:
- gRNA + Cas9
- Application:
- Protein Expression, Genome Editing with Engineered Nucleases
- Gene:
- Transcription Elongation Factor SPT5 (SUPT5H)
- NCBI Accession:
- NM_003169
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter, SFFV Promoter
- Expression:
- Stable, Transient
Synonyms and alternative names related to SUPT5H
- SPT5 homolog, DSIF elongation factor subunit (SUPT5H)
- transcription elongation factor SPT5 (LOC413814)
- Transcription elongation factor Spt5 (AT2G34210)
- transcription elongation factor Spt5 (spt5)
- transcription elongation factor spt5 (MGYG_08422)
- transcription elongation factor spt5 (TERG_05483)
- hypothetical protein (PGTG_18458)
- SPT5 homolog, DSIF elongation factor subunit (supt5h)
- SPT5 homolog, DSIF elongation factor subunit (Supt5h)
- SPT5 homolog, DSIF elongation factor subunit S homeolog (supt5h.S)
- CG7626 gene product from transcript CG7626-RA (Spt5)
- Transcription elongation factor SPT5 (spt-5)
- transcription elongation factor (SPT5)
- CaO19.1453
- CG7626
- dDSIF
- Dmel\\CG7626
- DSIF
- Dspt5
- dSpt5
- etID10129.15
- etID37101.15
- F13P17.5
- F13P17_5
- fb37g01
- fb95e05
- fog
- foggy
- SPT5
- Spt5
- spt5
- SPT5H
- spt5h
- Tat-CT1
- tat-ct1
- wu:fb37g01
- wu:fb95e05
- wu:fc10f02
Gene-IDs for different species
Protein level used designations for SUPT5H
- DRB sensitivity-inducing factor 160 kDa subunit
- DRB sensitivity-inducing factor large subunit
- DSIF large subunit
- DSIF p160
- Tat-cotransactivator 1 protein
- hSPT5
- transcription elongation factor SPT5
- transcription elongation factor Spt5
- transcription elongation factor spt5
- protein foggy
- transcription elongation regulator foggy
- CG7626-PA
- Spt5-PA
- Chromatin elongation factor SPT5
Proteomics products related to SUPT5H Gene
Other products related to SUPT5H such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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