Topoisomerase II alpha (Topoisomerase (DNA) II alpha 170kDa, TOP2A)
Short Description: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010].
More information related to gene Topoisomerase II alpha.
More information related to gene Topoisomerase II alpha.
Products related to Topoisomerase II alpha Gene:
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52 results
OriGene tl308699
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Human
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3753910
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg308699
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3733572
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene tf308699
shRNA
RNAi
Retroviral Vector
pRFP-C-RS
Chloramphenicol
U6 Promoter
RFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRFP-C-RS
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- RFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3713233
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene tl502310
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Mouse
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3704051
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg502310
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3684349
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr308699
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Human
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3650669
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 4 to 9 Business Days
OriGene tl710564
shRNA
RNAi
Lentiviral Vector
pGFP-C-shLenti
Chloramphenicol
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Rat
- Vector type:
- Lentiviral Vector
- Vector backbone:
- pGFP-C-shLenti
- Resistance Gene:
- Chloramphenicol
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3447844
$1,002.87
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tg710564
shRNA
RNAi
Retroviral Vector
pGFP-V-RS
Kanamycin
U6 Promoter
GFP tag
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pGFP-V-RS
- Resistance Gene:
- Kanamycin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Fusion Tag:
- GFP tag
- Expression:
- Transient, Stable
Catalog No. ABIN3504771
$707.85
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr502310
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Mouse
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3534652
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
OriGene tr710564
shRNA
RNAi
Retroviral Vector
pRS
Ampicillin
U6 Promoter
unconjugated
Transient
1
- Type:
- shRNA
- Application:
- RNA Interference
- Gene:
- Topoisomerase (DNA) II alpha 170kDa (TOP2A)
- Species:
- Rat
- Vector type:
- Retroviral Vector
- Vector backbone:
- pRS
- Resistance Gene:
- Ampicillin
- Selection Marker:
- Puromycin
- Promoter:
- U6 Promoter
- Expression:
- Transient, Stable
Catalog No. ABIN3435453
$874.17
Plus shipping costs $50.00
1 kit
Shipping to:
United States
Delivery in 16 to 17 Business Days
Synonyms and alternative names related to Topoisomerase II alpha
- DNA topoisomerase II alpha (TOP2A)
- DNA topoisomerase II, alpha isozyme (Bm1_08705)
- topoisomerase (DNA) II alpha (Top2a)
- DNA topoisomerase II alpha (Top2a)
- topoisomerase (DNA) II alpha (TOP2A)
- Zincin-like metalloproteases family protein (AT5G10540)
- DNA topoisomerase II alpha (top2a)
- F12B17.110
- F12B17_110
- fc08c07
- thimet metalloendopeptidase 2
- Top-2
- TOP-2
- TOP2
- TOP2A
- TP2A
- wu:fc08c07
Gene-IDs for different species
Protein level used designations for Topoisomerase II alpha
- DNA gyrase
- DNA topoisomerase (ATP-hydrolyzing)
- DNA topoisomerase 2-alpha
- DNA topoisomerase II, 170 kD
- DNA topoisomerase II, alpha isozyme
- DNA Topoisomerase II alpha
- topoisomerase (DNA) 2 alpha
- DNA topoisomeraseII_alpha
- topoisomerase (DNA) II alpha
- Thimet metalloendopeptidase 2
- Zincin-like metalloproteases family protein 2
- topoisomerase 2
Proteomics products related to Topoisomerase II alpha Gene
Other products related to Topoisomerase II alpha such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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