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TRAIL (Tumor Necrosis Factor (Ligand) Superfamily, Member 10, TNFSF10)

Short Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
More information related to gene TRAIL.

Products related to TRAIL Gene:

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64 results

Human TNFSF10 ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg230918 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5459656
$361.35
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Rat TNFSF10 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rr214556 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_145681,NP_663714
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5459661
$445.50
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human TNFSF10 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc230941 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_001190942,NP_001177871
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5459660
$163.35
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human TNFSF10 ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg230941 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5459657
$361.35
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human TNFSF10 ORF Clone in Mammalian Expression Vector (GFP tag)
OriGene rg207596 ORF PExp Mammalian Expression Vector pCMV6-AC-GFP Ampicillin CMV Promoter GFP tag Stable
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC-GFP
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Stable, Transient
Catalog No. ABIN5459655
$484.11
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human TNFSF10 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc207596 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_003810,NP_003801
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5459658
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human TNFSF10 ORF Clone in Mammalian Expression Vector (Myc-DYKDDDDK Tag)
OriGene rc230918 ORF PExp Mammalian Expression Vector pCMV6-Entry Kanamycin CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_001190943,NP_001177872
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5459659
$163.35
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 17 Business Days
Details
Details
Human TNFSF10 ORF Clone in Lentiviral Vector (Myc-DYKDDDDK Tag)
OriGene rc207596l1 ORF PExp Lentiviral Vector pLenti-C-Myc-DDK Chloramphenicol CMV Promoter Myc-DYKDDDDK Tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_003810,NP_003801
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-Myc-DDK
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN5459666
$594.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
Human TNFSF10 ORF Clone in Lentiviral Vector (GFP tag)
OriGene rc207596l2 ORF PExp Lentiviral Vector pLenti-C-mGFP Chloramphenicol CMV Promoter GFP tag Transient
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_003810,NP_003801
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-C-mGFP
Resistance Gene:
Chloramphenicol
Promoter:
CMV Promoter
Fusion Tag:
GFP tag
Expression:
Transient
Catalog No. ABIN5459662
$594.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
Details
Details
Human TNFSF10 ORF Clone in Mammalian Expression Vector (DYKDDDDK Tag)
ORF PExp Mammalian Expression Vector pcDNA3.1+C-(K)-DYK Ampicillin CMV Promoter DYKDDDDK Tag Transient
ISO 9001:2008
Type:
ORF
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_001190942
Gene ID:
8743 (Human, TNFSF10)
Vector type:
Mammalian Expression Vector
Vector backbone:
pcDNA3.1+C-(K)-DYK
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag
Expression:
Transient, Stable
Catalog No. ABIN4934456
$99.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 7 Business Days
Details
Details
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to TRAIL

  • TNF superfamily member 10 (TNFSF10)
  • tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10)
  • TNF superfamily member 10 (Tnfsf10)
  • tumor necrosis factor superfamily member 10 (TNFSF10)
  • TNF superfamily member 10 S homeolog (tnfsf10.S)
  • TNF superfamily member 10 (tnfsf10)
  • A330042I21Rik
  • AI448571
  • Apo-2L
  • APO-2L
  • apo-2l
  • APO2L
  • apo2l
  • CD253
  • cd253
  • Ly81
  • TL2
  • tl2
  • tnfsf10l2
  • TNLG6A
  • TRAIL
  • Trail
  • trail
  • trail1
  • xtrail1
  • zgc:92320

Gene-IDs for different species

Protein level used designations for TRAIL

  • Apo-2 ligand
  • TNF-related apoptosis inducing ligand TRAIL
  • chemokine tumor necrosis factor ligand superfamily member 10
  • tumor necrosis factor (ligand) family, member 10
  • tumor necrosis factor apoptosis-inducing ligand splice variant delta
  • tumor necrosis factor ligand superfamily member 10
  • TNF-related apoptosis inducing ligand
  • TNF-related apoptosis-inducing ligand
  • TRAIL/APO2L
  • tumor necrosis factor-related apoptosis-inducing ligand
  • TNF-related apoptosis-inducing ligand 1
  • tumor necrosis factor related apoptosis inducing ligand 1
  • DL2
  • TNFSF10-1
  • tumor necrosis factor (ligand) superfamily, member 10 like 2
  • tumor necrosis factor (ligand) superfamily, member 10
  • tumor necrosis factor ligand 6A
  • tumor necrosis factor superfamily member 10
Other products related to TRAIL such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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