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TRAIL (Tumor Necrosis Factor (Ligand) Superfamily, Member 10, TNFSF10)

Short Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
More information related to gene TRAIL.

Products related to TRAIL Gene:

64 results :

Human TNFSF10 ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5758378
Datasheet
Catalog No. ABIN5758378
Type:
ORF
Application:
Cloning
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Human
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Insert length:
846 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Mouse TNFSF10 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4458813
Datasheet
Catalog No. ABIN4458813
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425
Species:
Mouse
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Insert length:
876 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human TNFSF10 cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4482399
Datasheet
Catalog No. ABIN4482399
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Human
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Insert length:
846 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Rat TNFSF10 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_145681
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5268957
Datasheet
Catalog No. ABIN5268957
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_145681
Species:
Rat
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tnfsf10
Format:
Viral Particles
Storage:
-80 °C
Mouse TNFSF10 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5268955
Datasheet
Catalog No. ABIN5268955
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425
Species:
Mouse
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tnfsf10
Format:
Viral Particles
Storage:
-80 °C
Human TNFSF10 CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_003810
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5268953
Datasheet
Catalog No. ABIN5268953
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_003810
Species:
Human
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TNFSF10
Format:
Viral Particles
Storage:
-80 °C
Mouse TNFSF10 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5153391
Datasheet
Catalog No. ABIN5153391
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425
Species:
Mouse
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tnfsf10
Format:
Viral Particles
Storage:
-80 °C
Rat TNFSF10 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_145681
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5153393
Datasheet
Catalog No. ABIN5153393
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_145681
Species:
Rat
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Tnfsf10
Format:
Viral Particles
Storage:
-80 °C
Human TNFSF10 CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_003810
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5153389
Datasheet
Catalog No. ABIN5153389
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_003810
Species:
Human
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of TNFSF10
Format:
Viral Particles
Storage:
-80 °C
Mouse TNFSF10 cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425
Species:
Mouse
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4867611
Datasheet
Catalog No. ABIN4867611
Type:
cDNA
Application:
Cloning
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425
Species:
Mouse
Synonyms:
TNFSF10, Tnfsf10, tnfsf10.S, tnfsf10
Insert length:
4944 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to TRAIL

  • TNF superfamily member 10 (TNFSF10)
  • tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10)
  • TNF superfamily member 10 (Tnfsf10)
  • tumor necrosis factor superfamily member 10 (TNFSF10)
  • TNF superfamily member 10 S homeolog (tnfsf10.S)
  • TNF superfamily member 10 (tnfsf10)
  • A330042I21Rik
  • AI448571
  • Apo-2L
  • APO-2L
  • apo-2l
  • APO2L
  • apo2l
  • CD253
  • cd253
  • Ly81
  • TL2
  • tl2
  • tnfsf10l2
  • TNLG6A
  • TRAIL
  • Trail
  • trail
  • trail1
  • xtrail1
  • zgc:92320

Gene-IDs for different species

Protein level used designations for TRAIL

  • Apo-2 ligand
  • TNF-related apoptosis inducing ligand TRAIL
  • chemokine tumor necrosis factor ligand superfamily member 10
  • tumor necrosis factor (ligand) family, member 10
  • tumor necrosis factor apoptosis-inducing ligand splice variant delta
  • tumor necrosis factor ligand superfamily member 10
  • TNF-related apoptosis inducing ligand
  • TNF-related apoptosis-inducing ligand
  • TRAIL/APO2L
  • tumor necrosis factor-related apoptosis-inducing ligand
  • TNF-related apoptosis-inducing ligand 1
  • tumor necrosis factor related apoptosis inducing ligand 1
  • DL2
  • TNFSF10-1
  • tumor necrosis factor (ligand) superfamily, member 10 like 2
  • tumor necrosis factor (ligand) superfamily, member 10
  • tumor necrosis factor ligand 6A
  • tumor necrosis factor superfamily member 10
Other products related to TRAIL such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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