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TRAIL (Tumor Necrosis Factor (Ligand) Superfamily, Member 10, TNFSF10)

Short Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
More information related to gene TRAIL.

Products related to TRAIL Gene:

64 results

OriGene tg713116 shRNA RNAi Retroviral Vector pGFP-V-RS Kanamycin U6 Promoter GFP tag Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable
Catalog No. ABIN3507313
$707.85
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tr502321 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Mouse
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3534663
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene tr713116 shRNA RNAi Retroviral Vector pRS Ampicillin U6 Promoter unconjugated Transient
Type:
shRNA
Application:
RNA Interference
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Rat
Vector type:
Retroviral Vector
Vector backbone:
pRS
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Expression:
Transient, Stable
Catalog No. ABIN3437995
$874.17
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene kn517993 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3258213
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene kn407596 gRNA + Cas9 GEEN Mammalian Expression Vector pCas-Guide Ampicillin U6 Promoter Myc-DYKDDDDK Tag Transient
Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCas-Guide
Resistance Gene:
Ampicillin
Promoter:
U6 Promoter, Enhanced CMV Promoter
Fusion Tag:
Myc-DYKDDDDK Tag
Expression:
Transient
Catalog No. ABIN3258212
$1,640.43
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene sr408402 RNAi TNFSF10 Species: Mouse HPLC purified
Application:
RNA Interference
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10
Species:
Mouse
Purification:
HPLC purified
Catalog No. ABIN3282344
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene sc321920 cDNA PExp Mammalian Expression Vector pCMV6-AC Ampicillin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_003810,NP_003801
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-AC
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient, Stable
Catalog No. ABIN3319448
$297.00
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 4 to 9 Business Days
OriGene sr514266 RNAi TNFSF10 Species: Rat HPLC purified
Application:
RNA Interference
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10
Species:
Rat
Purification:
HPLC purified
Catalog No. ABIN3315756
$512.82
Plus shipping costs $50.00
1 kit
Shipping to: United States
Delivery in 16 to 17 Business Days
OriGene mc209584 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_009425,NP_033451
Species:
Mouse
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3337193
$326.70
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
OriGene rn214556 cDNA PExp Mammalian Expression Vector pCMV6-Entry Kanamycin Enhanced CMV Promoter unconjugated Transient
Type:
cDNA
Application:
Protein Expression
Gene:
Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
NCBI Accession:
NM_145681,NP_663714
Species:
Rat
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV6-Entry
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
Enhanced CMV Promoter
Expression:
Transient
Catalog No. ABIN3337194
$475.20
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 21 to 22 Business Days
  • Type
    • Plasmid
    • Primer
  • Supplier
    • OriGene
    • antibodies-online
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Rat
    • Mouse
  • Application
    • Protein Expression (PExp)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
    • RNA Interference (RNAi)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • Myc-DYKDDDDK Tag
    • His tag
    • DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
  • Vector Backbone
    • pCMV6-Entry
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-AC-GFP
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRS
    • pcDNA3.1+C-(K)-DYK
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-XL5
    • pDONR223
    • pRFP-C-RS
  • Vector
    • Mammalian Expression Vector
    • Lentiviral Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Ampicillin
    • Kanamycin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Neomycin
    • Puromycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • Enhanced CMV Promoter
    • PGK Promoter
    • SFFV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to TRAIL

  • TNF superfamily member 10 (TNFSF10)
  • tumor necrosis factor (ligand) superfamily, member 10 (Tnfsf10)
  • TNF superfamily member 10 (Tnfsf10)
  • tumor necrosis factor superfamily member 10 (TNFSF10)
  • TNF superfamily member 10 S homeolog (tnfsf10.S)
  • TNF superfamily member 10 (tnfsf10)
  • A330042I21Rik
  • AI448571
  • Apo-2L
  • APO-2L
  • apo-2l
  • APO2L
  • apo2l
  • CD253
  • cd253
  • Ly81
  • TL2
  • tl2
  • tnfsf10l2
  • TNLG6A
  • TRAIL
  • Trail
  • trail
  • trail1
  • xtrail1
  • zgc:92320

Gene-IDs for different species

Protein level used designations for TRAIL

  • Apo-2 ligand
  • TNF-related apoptosis inducing ligand TRAIL
  • chemokine tumor necrosis factor ligand superfamily member 10
  • tumor necrosis factor (ligand) family, member 10
  • tumor necrosis factor apoptosis-inducing ligand splice variant delta
  • tumor necrosis factor ligand superfamily member 10
  • TNF-related apoptosis inducing ligand
  • TNF-related apoptosis-inducing ligand
  • TRAIL/APO2L
  • tumor necrosis factor-related apoptosis-inducing ligand
  • TNF-related apoptosis-inducing ligand 1
  • tumor necrosis factor related apoptosis inducing ligand 1
  • DL2
  • TNFSF10-1
  • tumor necrosis factor (ligand) superfamily, member 10 like 2
  • tumor necrosis factor (ligand) superfamily, member 10
  • tumor necrosis factor ligand 6A
  • tumor necrosis factor superfamily member 10
Other products related to TRAIL such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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