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WASP (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia), WAS)

Short Description: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. [provided by RefSeq, Jul 2008].
More information related to gene WASP.

Products related to WASP Gene:

58 results :

Human WAS ORF Clone in Cloning Vector
ORF Clon Cloning Vector pORF Spectinomycin unconjugated Transient
Type:
ORF
Application:
Cloning
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Species:
Human
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Catalog No. ABIN5758828
Datasheet
Catalog No. ABIN5758828
Type:
ORF
Application:
Cloning
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Species:
Human
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Insert length:
1509 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient
Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Human WAS cDNA Clone in Mammalian Expression Vector (HA tag)
cDNA PExp Mammalian Expression Vector pPM-C-HA Kanamycin CMV Promoter HA tag Stable
Type:
cDNA
Application:
Protein Expression
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Species:
Human
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Catalog No. ABIN4483076
Datasheet
Catalog No. ABIN4483076
Type:
cDNA
Application:
Protein Expression
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Species:
Human
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Insert length:
1509 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient
Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Mouse WAS CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_009515
Species:
Mouse
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5269771
Datasheet
Catalog No. ABIN5269771
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_009515
Species:
Mouse
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Was
Format:
Viral Particles
Storage:
-80 °C
Human WAS CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_000377
Species:
Human
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5269769
Datasheet
Catalog No. ABIN5269769
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_000377
Species:
Human
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of WAS
Format:
Viral Particles
Storage:
-80 °C
Rat WAS CRISPR gRNA + Cas9 in Lenti Particles
gRNA + Cas9 PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_001108248
Species:
Rat
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Catalog No. ABIN5269773
Datasheet
Catalog No. ABIN5269773
Type:
gRNA + Cas9
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_001108248
Species:
Rat
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient
Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Was
Format:
Viral Particles
Storage:
-80 °C
Rat WAS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_001108248
Species:
Rat
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5154207
Datasheet
Catalog No. ABIN5154207
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_001108248
Species:
Rat
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Was
Format:
Viral Particles
Storage:
-80 °C
Mouse WAS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_009515
Species:
Mouse
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5154205
Datasheet
Catalog No. ABIN5154205
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_009515
Species:
Mouse
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Was
Format:
Viral Particles
Storage:
-80 °C
Human WAS CRISPR gRNA in Lenti Particles
gRNA PExp, GEEN Lentiviral Vector pLenti-U6-sgRNA-PGK-Neo Ampicillin U6 Promoter unconjugated Stable
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_000377
Species:
Human
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Catalog No. ABIN5154203
Datasheet
Catalog No. ABIN5154203
Type:
gRNA
Application:
Protein Expression, Genome Editing with Engineered Nucleases
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
NCBI Accession:
NM_000377
Species:
Human
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of WAS
Format:
Viral Particles
Storage:
-80 °C
Human WAS cDNA Clone in Bacterial Expression Vector (His-GST)
cDNA Clon Bacterial Expression Vector pPB-His-GST Kanamycin T7 Promoter His-GST Transient
Type:
cDNA
Application:
Cloning
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Catalog No. ABIN4843153
Datasheet
Catalog No. ABIN4843153
Type:
cDNA
Application:
Cloning
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Species:
Human
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Insert length:
1509 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient
Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Human WAS cDNA Clone in Bacterial Expression Vector (His tag)
cDNA Clon Bacterial Expression Vector pPB-N-His Kanamycin T7 Promoter His tag Transient
Type:
cDNA
Application:
Cloning
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Species:
Human
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Catalog No. ABIN4626547
Datasheet
Catalog No. ABIN4626547
Type:
cDNA
Application:
Cloning
Gene:
Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS)
Species:
Human
Synonyms:
WAS, LOC5578888, CpipJ_CPIJ006699, Was, was.L, wasb
Insert length:
1509 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient
Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
  • Type
    • Plasmid
    • Primer
  • Supplier
    • antibodies-online
    • OriGene
    • GenScript
    • ProteoGenix
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Application
    • Protein Expression (PExp)
    • RNA Interference (RNAi)
    • Genome Editing with Engineered Nucleases (GEEN)
    • Cloning (Clon)
  • Conjugate
    • Un-conjugated
    • GFP tag
    • His tag
    • Myc-DYKDDDDK Tag
    • HA tag
    • His-GST
    • His-MBP
    • RFP tag
    • DYKDDDDK Tag
  • Vector Backbone
    • pLenti-U6-sgRNA-PGK-Neo
    • pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
    • pCMV6-Entry
    • pGFP-C-shLenti
    • pGFP-V-RS
    • pORF
    • pPB-His-GST
    • pPB-His-MBP
    • pPB-N-His
    • pPM-C-HA
    • pPM-C-His
    • pRFP-C-RS
    • pRS
    • pCas-Guide
    • pLenti-C-Myc-DDK
    • pLenti-C-mGFP
    • pCMV6-AC
    • pCMV6-AC-GFP
    • pDONR223
    • pcDNA3.1+C-(K)-DYK
  • Vector
    • Lentiviral Vector
    • Mammalian Expression Vector
    • Bacterial Expression Vector
    • Retroviral Vector
    • Cloning Vector
    • Gateway Cloning Vector
  • Insert
    • cDNA
    • ORF
    • shRNA
    • gRNA + Cas9
    • gRNA
  • Type of Oligonucleotide
    • siRNA Oligo
  • Bacterial Resistance
    • Kanamycin
    • Ampicillin
    • Chloramphenicol
    • Spectinomycin
  • Expression Type
    • Transient
    • Stable
  • Selectable Marker
    • Puromycin
    • Neomycin
  • Promoter
    • U6 Promoter
    • CMV Promoter
    • T7 Promoter
    • PGK Promoter
    • SFFV Promoter
    • Enhanced CMV Promoter
  • Format
    • Lyophilized
    • Liquid
    • Viral Particles

Synonyms and alternative names related to WASP

  • Wiskott-Aldrich syndrome (WAS)
  • neural Wiskott-Aldrich syndrome protein (LOC5578888)
  • wiskott-aldrich syndrome protein (CpipJ_CPIJ006699)
  • Wiskott-Aldrich syndrome (Was)
  • Wiskott-Aldrich syndrome L homeolog (was.L)
  • Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b (wasb)
  • IMD2
  • imd2
  • SCNX
  • THC
  • thc
  • THC1
  • thc1
  • U42471
  • was
  • WASP
  • WASp
  • Wasp
  • wasp
  • wu:fk81c08
  • zgc:64164

Gene-IDs for different species

Protein level used designations for WASP

  • eczema-thrombocytopenia
  • thrombocytopenia 1 (X-linked)
  • wiskott-Aldrich syndrome protein
  • wiskott-aldrich syndrome protein
  • Wiskott-Aldrich syndrome homolog
  • wiskott-Aldrich syndrome protein homolog
  • Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
  • Wiskott-Aldrich syndrome L homeolog
  • wiskott-Aldrich syndrome L homeolog
  • wasp1
Other products related to WASP such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com
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