ABCA2 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 2, ABCA2)

Short Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
More information related to gene ABCA2.
Products related to ABCA2 Gene:
79 Products
Type
  • 74
  • 5
Species
  • 31
  • 24
  • 22
  • 2
Oligo-Type
  • 5
Insert
  • 27
  • 20
  • 11
  • 8
  • 6
Vector
  • 26
  • 23
  • 12
  • 9
  • 3
Vector Backbone
  • 6
  • 6
  • 6
  • 6
  • 3
Fusion tag
  • 29
  • 10
  • 9
  • 8
  • 5
Resistance Gene
  • 33
  • 31
  • 6
  • 4
  • 2
Selectable Marker
  • 26
  • 25
Promoter
  • 30
  • 19
  • 12
  • 8
  • 6
Expression Type
  • 73
  • 48
Application
  • 37
  • 25
  • 16
  • 15
Format
  • 31
  • 25
  • 16
  • 7
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The ATP-binding cassette, sub-family A (ABC1), member 2 ORF clone is provided in a Gateway adapted entry vector for fast and convenient transfer to any compatible expression vector.

Type:
ORF
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
Gene ID:
20 (Human, ABCA2)
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Gateway Cloning Vector
Vector backbone:
pENTR223-1
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3417660
€265.49
1 vial
Plus shipping costs €45.00
Delivery in 6 to 8 Business Days
Supplier: Log in to see

ORF Cloning-Vector holds the gene between an AflII and EcoRV cut site.

Type:
ORF
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_001606
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5737605
€309.73
1 μg
Plus shipping costs €45.00
Delivery in 3 to 4 Business Days
Supplier: Log in to see

siRNA (27 mer) kit with 3 gene-specific unique siRNA duplexes and negative control for gene knockdown.

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2
Species:
Mouse (Murine)
Synonyms:
ABC2, AI413825, Abc2, D2H0S1474E, mKIAA1062, si:dkey-266h7.1
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Abca2 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3350337
€345.13
1 kit
Plus shipping costs €45.00
Will be delivered in 16 Business Days
Supplier: Log in to see

siRNA (27 mer) kit with 3 gene-specific unique siRNA duplexes and negative control for gene knockdown.

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2
Species:
Human
Synonyms:
ABC2, AI413825, Abc2, D2H0S1474E, mKIAA1062, si:dkey-266h7.1
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • ABCA2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3339808
€345.13
1 kit
Plus shipping costs €45.00
Will be delivered in 16 Business Days
Supplier: Log in to see

siRNA (27 mer) kit with 3 gene-specific unique siRNA duplexes and negative control for gene knockdown.

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2
Species:
Rat (Rattus)
Synonyms:
ABC2, AI413825, Abc2, D2H0S1474E, mKIAA1062, si:dkey-266h7.1
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Abca2 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3361138
€345.13
1 kit
Plus shipping costs €45.00
Will be delivered in 16 Business Days
Supplier: Log in to see

Individual gRNA against ABCA2 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (Cas9 required separately)

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_001606
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCA2
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113236
€349.56
300 μL
Plus shipping costs €45.00 and €20.00 dry ice
Available
Supplier: Log in to see

Individual gRNA against Abca2 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (Cas9 required separately)

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_024396
Species:
Rat (Rattus)
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abca2
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113240
€349.56
300 μL
Plus shipping costs €45.00 and €20.00 dry ice
Available
Supplier: Log in to see

Individual gRNA against Abca2 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (Cas9 required separately)

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_007379
Species:
Mouse (Murine)
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abca2
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113238
€349.56
300 μL
Plus shipping costs €45.00 and €20.00 dry ice
Available
Supplier: Log in to see

siRNA to inhibit ABCA2 expression using RNA interference.

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2
Gene ID:
20 (Human, ABCA2)
Synonyms:
ABC2, AI413825, Abc2, D2H0S1474E, mKIAA1062, si:dkey-266h7.1
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5789178
€404.49
15 nmol
Plus shipping costs €45.00
Delivery in 16 to 26 Business Days
Supplier: Log in to see

siRNA to inhibit ABCA2 expression using RNA interference.

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2
Gene ID:
79248 (Rat (Rattus), ABCA2)
Synonyms:
ABC2, AI413825, Abc2, D2H0S1474E, mKIAA1062, si:dkey-266h7.1
Purification:
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Components:
This product is provided as two 5 nmol vials (10 nmol), three 5 nmol vials (15 nmol) or 2x three 5 nmol vials (30 nmol) of lyophilized siRNA oligo duplexes. Each vial contains slightly different sequences to ensure full knockout of the gene. Each vial contains slightly different sequences to ensure full knockout of the gene. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. The siRNA oligos are also chemically modified (2'-OMe) for increased stability and enhanced knockdown in vitro and in vivo.
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN5789177
€404.49
15 nmol
Plus shipping costs €45.00
Delivery in 16 to 26 Business Days
Supplier: Log in to see

transEDIT-dual CRISPR target gene set - with 3 vectors containing two gRNAs in each vector plus a negative control (glycerol stock)

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
Gene ID:
20 (Human, ABCA2)
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5050910

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5031965
€438.05
1 set
Plus shipping costs €45.00
Will be delivered in 16 Business Days
Supplier: Log in to see

Individual gRNA against ABCA2 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (sgRNA and Cas9 in a single vector)

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_001606
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCA2
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228568
€438.05
300 μL
Plus shipping costs €45.00 and €20.00 dry ice
Available
Supplier: Log in to see

Mammalian expression of Human ABCA2 with HA tag

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_001606
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Insert length:
903 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4486699
€438.05
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Bacterial expression of Human ABCA2 with His tag

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_001606
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Insert length:
903 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-C-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient

Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4778391
€438.05
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Individual gRNA against Abca2 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (sgRNA and Cas9 in a single vector)

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_007379
Species:
Mouse (Murine)
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abca2
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228570
€438.05
300 μL
Plus shipping costs €45.00 and €20.00 dry ice
Available
Supplier: Log in to see

Mammalian expression of Human ABCA2 with His tag

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_001606
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Insert length:
903 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4421613
€438.05
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Bacterial expression of Human ABCA2 with His tag

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_001606
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Insert length:
903 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient

Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4630170
€438.05
500 ng
Plus shipping costs €45.00
Delivery in 11 to 21 Business Days
Supplier: Log in to see

Individual gRNA against Abca2 in Lentiviral Particles with a Titer of >1x10e7 IU/mL. (sgRNA and Cas9 in a single vector)

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
NCBI Accession:
NM_024396
Species:
Rat (Rattus)
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abca2
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228572
€438.05
300 μL
Plus shipping costs €45.00 and €20.00 dry ice
Available
Supplier: Log in to see

Prokaryotic expression plasmid for cDNA.

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient

Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5772619
€438.05
500 ng
Plus shipping costs €45.00
Delivery in 3 to 4 Business Days
Supplier: Log in to see

Prokaryotic expression plasmid for cDNA.

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2)
Species:
Human
Synonyms:
ABCA2, Abca2, abca2
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient

Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5772620
€438.05
500 ng
Plus shipping costs €45.00
Delivery in 3 to 4 Business Days
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Synonyms and alternative names related to ABCA2

  • ATP binding cassette subfamily A member 2 (ABCA2)
  • ATP-binding cassette, sub-family A (ABC1), member 2 (Abca2)
  • ATP binding cassette subfamily A member 2 (Abca2)
  • ATP binding cassette subfamily A member 2 (abca2)
  • ATP-binding cassette, sub-family A (ABC1), member 2 (abca2)
  • ABC2
  • Abc2
  • AI413825
  • D2H0S1474E
  • mKIAA1062
  • si:dkey-266h7.1

Gene-IDs for different species

GENE IDSPECIES
20 Homo sapiens
11305 Mus musculus
79248 Rattus norvegicus
426955 Gallus gallus
480669 Canis lupus familiaris
100017432 Monodelphis domestica
100067889 Equus caballus
100231140 Taeniopygia guttata
100299651 Bos taurus
100498548 Xenopus (Silurana) tropicalis
100731855 Cavia porcellus
100006090 Danio rerio

Protein level used designations for ABCA2

  • ATP-binding cassette 2
  • ATP-binding cassette sub-family A member 2
  • ATP-binding cassette transporter 2
  • ATP-binding cassette, sub-family A, member 2
  • ATP-binding cassette, sub-family A (ABC1), member 2
  • ATP-binding cassette sub-family A member 2-like
Other products related to ABCA2 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com