ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4, ABCA4)

Short Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Jul 2008].
More information related to gene ABCA4.
Products related to ABCA4 Gene:
Type
  • 66
  • 2
Species
  • 23
  • 22
  • 21
  • 2
Application
  • 34
  • 20
  • 16
  • 13
Fusion tag
  • 27
  • 8
  • 7
  • 6
  • 6
Vector Backbone
  • 6
  • 6
  • 6
  • 4
  • 3
Vector
  • 25
  • 20
  • 9
  • 8
  • 2
Insert
  • 22
  • 18
  • 10
  • 8
  • 6
Oligo-Type
  • 2
Resistance Gene
  • 31
  • 23
  • 8
  • 4
  • 2
Expression Type
  • 64
  • 42
Selectable Marker
  • 26
  • 18
Promoter
  • 28
  • 14
  • 9
  • 8
  • 8
Format
  • 24
  • 18
  • 17
  • 9
68 Products

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
798993 (Zebrafish (Danio rerio), ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Mammalian Expression Vector
Vector backbone:
pExpress-1
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4070099
$107.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
798993 (Zebrafish (Danio rerio), ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Mammalian Expression Vector
Vector backbone:
pExpress-1
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4070100
$147.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
11304 (Mouse, ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Mammalian Expression Vector
Vector backbone:
pCMV-SPORT6
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • T7
  • Sp6
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3807455
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
ORF
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
24 (Human, ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Gateway Cloning Vector
Vector backbone:
pENTR223-1
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3417774
$308.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
ORF
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
24 (Human, ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Gateway Cloning Vector
Vector backbone:
pENTR223-1
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3417480
$308.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
NCBI Accession:
NM_001107721
Species:
Rat
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abca4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113246
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
NCBI Accession:
NM_000350
Species:
Human
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCA4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113242
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
NCBI Accession:
NM_007378
Species:
Mouse
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abca4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113244
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4
Species:
Human
Synonyms:
ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1, AW050280, Abc10, Abcr, D430003I15Rik, RmP, abcr, ffm, rmp, rp19, stgd, abc10, armd2, cord3, stgd1, zgc:91823
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • ABCA4 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3339812
$440.00
1 kit
Plus shipping costs $45.00
Delivery in 4 to 8 Business Days

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4
Species:
Mouse
Synonyms:
ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1, AW050280, Abc10, Abcr, D430003I15Rik, RmP, abcr, ffm, rmp, rp19, stgd, abc10, armd2, cord3, stgd1, zgc:91823
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Abca4 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3350304
$440.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
24 (Human, ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5052259

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5033314
$503.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
NCBI Accession:
NM_000350
Species:
Human
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCA4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228574
$520.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
NCBI Accession:
NM_001107721
Species:
Rat
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abca4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228578
$520.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
NCBI Accession:
NM_007378
Species:
Mouse
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abca4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228576
$520.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
24 (Human, ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3474040

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN3474039
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
310836 (Rat, ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3474040

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN4183857
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Gene ID:
11304 (Mouse, ABCA4)
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3474040

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN3775386
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Species:
Human
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948188

Components:
  • Gene-specific shRNA expression pRFP-C-RS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pGFP-VRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3719525
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Species:
Human
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948187

Components:
  • Gene-specific shRNA in pGFPC-shLenti vector, 4 unique constructs per gene, 5 ug per vial.
  • HuSH 29-mer Scrambled in pGFP-C-shLenti 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3739864
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4)
Species:
Mouse
Synonyms:
ABCA4, Abca4, abca4, abca4.L, abca4a
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948188

Components:
  • Gene-specific shRNA expression pRFP-C-RS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pGFP-VRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3677783
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days
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  • 1

Synonyms and alternative names related to ABCA4

  • ATP binding cassette subfamily A member 4 (ABCA4)
  • ATP-binding cassette, sub-family A (ABC1), member 4 (Abca4)
  • ATP binding cassette subfamily A member 4 (Abca4)
  • ATP binding cassette subfamily A member 4 (abca4)
  • ATP binding cassette subfamily A member 4 L homeolog (abca4.L)
  • ATP-binding cassette, sub-family A (ABC1), member 4a (abca4a)
  • abc10
  • ABC10
  • Abc10
  • Abcr
  • abcr
  • ABCR
  • ARMD2
  • armd2
  • AW050280
  • CORD3
  • cord3
  • D430003I15Rik
  • ffm
  • FFM
  • RmP
  • rmp
  • RMP
  • rp19
  • RP19
  • STGD
  • stgd
  • STGD1
  • stgd1
  • zgc:91823

Gene-IDs for different species

GENE IDSPECIES
24 Homo sapiens
11304 Mus musculus
281584 Bos taurus
310836 Rattus norvegicus
424490 Gallus gallus
444852 Canis lupus familiaris
496442 Xenopus (Silurana) tropicalis
745972 Pan troglodytes
100393904 Callithrix jacchus
100440877 Pongo abelii
100479076 Ailuropoda melanoleuca
497268 Xenopus laevis
100605850 Nomascus leucogenys
100725431 Cavia porcellus
100058746 Equus caballus
798993 Danio rerio

Protein level used designations for ABCA4

  • ATP binding cassette transporter
  • ATP-binding cassette sub-family A member 4
  • ATP-binding cassette transporter, retinal-specific
  • ATP-binding transporter, retina-specific
  • RIM ABC transporter
  • RIM protein
  • photoreceptor rim protein
  • retina-specific ABC transporter
  • retinal-specific ATP-binding cassette transporter
  • stargardt disease protein
  • ATP-binding cassette 10
  • Rim protein
  • ATP-binding cassette, sub-family A (ABC1), member 4
  • ATP-binding cassette, sub-family A member 4
  • retinal-specific ATP transporter ABCA4
  • retinal-specific ATP-binding cassette transporter-like
  • ATP-binding cassette, sub-family A, member 4
  • retinal ABCA4 transporter
  • ATP-binding cassette, sub-family A (ABC1), member 4a
Other products related to ABCA4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com