ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11, ABCB11)

Short Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008].
More information related to gene ABCB11.
Products related to ABCB11 Gene:
Type
  • 65
  • 3
Species
  • 28
  • 20
  • 20
Application
  • 35
  • 19
  • 16
  • 10
Fusion tag
  • 25
  • 10
  • 7
  • 6
  • 6
Vector Backbone
  • 6
  • 6
  • 4
  • 3
  • 3
Vector
  • 27
  • 17
  • 9
  • 8
  • 2
Insert
  • 19
  • 16
  • 14
  • 8
  • 6
Oligo-Type
  • 3
Resistance Gene
  • 27
  • 22
  • 12
  • 4
  • 2
Expression Type
  • 63
  • 41
Selectable Marker
  • 24
  • 19
Promoter
  • 28
  • 18
  • 9
  • 8
  • 6
Format
  • 28
  • 18
  • 17
  • 5
68 Products

Type:
ORF
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Gene ID:
27413 (Mouse, ABCB11)
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Gateway Cloning Vector
Vector backbone:
pENTR223-1
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3433509
$308.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
ORF
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Gene ID:
27413 (Mouse, ABCB11)
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Gateway Cloning Vector
Vector backbone:
pENTR223-1
Resistance Gene:
Spectinomycin

Sequencing Primer:
  • T7
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN3433981
$308.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
NCBI Accession:
NM_021022
Species:
Mouse
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abcb11
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113274
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
NCBI Accession:
NM_003742
Species:
Human
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCB11
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113272
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
NCBI Accession:
NM_031760
Species:
Rat
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abcb11
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113276
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11
Species:
Mouse
Synonyms:
ABCB11, Bsep, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP, Lith1, BSEP/SPGP, Spgp
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Abcb11 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3349517
$440.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11
Species:
Human
Synonyms:
ABCB11, Bsep, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP, Lith1, BSEP/SPGP, Spgp
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • ABCB11 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3345448
$440.00
1 kit
Plus shipping costs $45.00
Delivery in 4 to 8 Business Days

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11
Species:
Rat
Synonyms:
ABCB11, Bsep, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP, Lith1, BSEP/SPGP, Spgp
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Abcb11 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3360240
$440.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Gene ID:
8647 (Human, ABCB11)
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5064250

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5045305
$503.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
NCBI Accession:
NM_003742
Species:
Human
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCB11
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228606
$520.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
NCBI Accession:
NM_021022
Species:
Mouse
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abcb11
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228608
$520.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA + Cas9
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
NCBI Accession:
NM_031760
Species:
Rat
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
U6 Promoter, SFFV Promoter
Expression:
Stable, Transient

Sequencing Primer:
  • U6 Forward Primer: 5'--TACGTCCAAGGTCGGGCAGGAAGA--3'
Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abcb11
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5228610
$520.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
ORF
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
NCBI Accession:
NM_021022
Species:
Mouse
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Insert length:
3966 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5737624
$651.00
1 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days

Type:
ORF
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
NCBI Accession:
NM_031760
Species:
Rat
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Insert length:
3966 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5737625
$651.00
1 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Gene ID:
8647 (Human, ABCB11)
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3456341

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN3456340
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Gene ID:
27413 (Mouse, ABCB11)
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Lentiviral Vector
Vector backbone:
pZIP-mCMV-ZsGreen
Resistance Gene:
Ampicillin
Selection Marker:
Puromycin
Promoter:
mCMV Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Empty vector controls:
ABIN5691888
Viral particles:
ABIN3456341

Components:
3 separate shRNA clones and a non-targeting control
Format:
Glycerol Stock
Buffer:
E. coli bacterial culture in LB-Lennox (low salt) broth with 8 % glycerol.
Storage:
-80 °C
Catalog No. ABIN3798374
$703.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Species:
Human
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948188

Components:
  • Gene-specific shRNA expression pRFP-C-RS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pGFP-VRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3719521
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Species:
Human
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Retroviral Vector
Vector backbone:
pGFP-V-RS
Resistance Gene:
Kanamycin
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
GFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948187

Components:
  • Gene-specific shRNA in pGFPC-shLenti vector, 4 unique constructs per gene, 5 ug per vial.
  • HuSH 29-mer Scrambled in pGFP-C-shLenti 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3739860
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Species:
Rat
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948188

Components:
  • Gene-specific shRNA expression pRFP-C-RS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pGFP-VRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3491828
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
shRNA
Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11)
Species:
Mouse
Synonyms:
ABCB11, LOC100489744, LOC100565276, EDI_111220, EDI_272930, abcb11, Abcb11
Vector type:
Retroviral Vector
Vector backbone:
pRFP-C-RS
Resistance Gene:
Chloramphenicol
Selection Marker:
Puromycin
Promoter:
U6 Promoter
Fusion Tag:
RFP tag
Expression:
Transient, Stable

Empty vector controls:
ABIN4948188

Components:
  • Gene-specific shRNA expression pRFP-C-RS vectors, 5 ug plasmid DNA per vial.
  • Four unique constructs per gene.
  • HuSH 29-mer NonEffective Scrambled pGFP-VRS 5 ug plasmid DNA.
Format:
Lyophilized
Storage:
4 °C/-20 °C
Catalog No. ABIN3675054
$715.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days
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  • 1

Synonyms and alternative names related to ABCB11

  • ATP binding cassette subfamily B member 11 (ABCB11)
  • bile salt export pump (LOC100489744)
  • bile salt export pump (LOC100565276)
  • bile salt export pump (EDI_111220)
  • bile salt export pump (EDI_272930)
  • bile salt export pump (abcb11)
  • ATP binding cassette subfamily B member 11 (Abcb11)
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11 (Abcb11)
  • ABC16
  • ABCB11
  • BRIC2
  • Bsep
  • BSEP
  • BSEP/SPGP
  • Lith1
  • PFIC-2
  • PFIC2
  • PGY4
  • SPGP
  • Spgp

Gene-IDs for different species

GENE IDSPECIES
424170 Gallus gallus
470717 Pan troglodytes
488390 Canis lupus familiaris
531150 Bos taurus
100024107 Monodelphis domestica
100052359 Equus caballus
100083318 Ornithorhynchus anatinus
100404882 Callithrix jacchus
100454135 Pongo abelii
100473353 Ailuropoda melanoleuca
100489744 Xenopus (Silurana) tropicalis
100518154 Sus scrofa
100543935 Meleagris gallopavo
100565276 Anolis carolinensis
100590891 Nomascus leucogenys
5879080 Entamoeba dispar SAW760
5914265 Entamoeba dispar SAW760
100136688 Oncorhynchus mykiss
100337637 Cavia porcellus
8647 Homo sapiens
27413 Mus musculus
100008767 Oryctolagus cuniculus
83569 Rattus norvegicus

Protein level used designations for ABCB11

  • ATP-binding cassette, sub-family B (MDR/TAP), member 11
  • bile salt export pump
  • bile salt export pump-like
  • ABC member 16, MDR/TAP subfamily
  • ATP-binding cassette sub-family B member 11
  • progressive familial intrahepatic cholestasis 2
  • sister p-glycoprotein
  • ATP-binding cassette, sub-family B, member 11
  • sister of P-glycoprotein
  • liver bile salt export pump
Other products related to ABCB11 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com