ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4, ABCB4)

Short Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined\; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008].
More information related to gene ABCB4.
Products related to ABCB4 Gene:
Type
  • 88
  • 3
Species
  • 40
  • 27
  • 22
  • 2
Application
  • 49
  • 21
  • 19
  • 16
Fusion tag
  • 28
  • 14
  • 11
  • 9
  • 8
Vector Backbone
  • 7
  • 6
  • 6
  • 6
  • 5
Vector
  • 33
  • 29
  • 12
  • 9
  • 5
Insert
  • 31
  • 23
  • 18
  • 8
  • 6
Oligo-Type
  • 3
Resistance Gene
  • 35
  • 34
  • 16
  • 3
  • 2
Expression Type
  • 86
  • 50
Selectable Marker
  • 28
  • 26
Promoter
  • 32
  • 28
  • 12
  • 8
  • 7
Format
  • 38
  • 27
  • 18
  • 8
91 Products

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
Gene ID:
100136865 (Zebrafish (Danio rerio), ABCB4)
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Vector type:
Mammalian Expression Vector
Vector backbone:
pExpress-1
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4070905
$107.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Protein Expression, Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
Gene ID:
100136865 (Zebrafish (Danio rerio), ABCB4)
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Vector type:
Mammalian Expression Vector
Vector backbone:
pExpress-1
Resistance Gene:
Ampicillin
Promoter:
Enhanced CMV Promoter
Expression:
Transient

Sequencing Primer:
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4070906
$147.00
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
Gene ID:
18670 (Mouse, ABCB4)
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Vector type:
Cloning Vector
Vector backbone:
pCR4-TOPO
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin

Sequencing Primer:
  • T7
  • T3
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4003507
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
Gene ID:
5244 (Human, ABCB4)
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Vector type:
Cloning Vector
Vector backbone:
pBluescriptR
Resistance Gene:
Ampicillin

Sequencing Primer:
  • T7
  • T3
  • M13(-21)
  • M13 rev
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN4211312
$162.44
1 vial
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_018850
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of ABCB4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113278
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_008830
Species:
Mouse
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abcb4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113280
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Type:
gRNA
Application:
Genome Editing with Engineered Nucleases, Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_012690
Species:
Rat
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Vector type:
Lentiviral Vector
Vector backbone:
pLenti-U6-sgRNA-PGK-Neo
Resistance Gene:
Ampicillin
Selection Marker:
Neomycin
Promoter:
U6 Promoter, PGK Promoter
Expression:
Stable, Transient

Components:
Lentiviral particles with an individual gRNA (300 μL) for a specific sequence of Abcb4
Format:
Viral Particles
Storage:
-80 °C
Catalog No. ABIN5113282
$420.00
300 μL
Plus shipping costs $45.00 and $24.00 dry ice
Available

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4
Species:
Mouse
Synonyms:
ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3, zgc:172149, Mdr2, Pgy-2, Pgy2, mdr-2, Pgy3, ABCB4a, DEFB1, PGP3, ABCB4, RUNDC3B
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Abcb4 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3349428
$440.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4
Species:
Human
Synonyms:
ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3, zgc:172149, Mdr2, Pgy-2, Pgy2, mdr-2, Pgy3, ABCB4a, DEFB1, PGP3, ABCB4, RUNDC3B
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • ABCB4 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3343265
$440.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Application:
RNA Interference
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4
Species:
Rat
Synonyms:
ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3, zgc:172149, Mdr2, Pgy-2, Pgy2, mdr-2, Pgy3, ABCB4a, DEFB1, PGP3, ABCB4, RUNDC3B
Purification:
HPLC purified
Sequence:
Available with shipment
Components:
  • Abcb4 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each
  • Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmol
  • RNAse free siRNA Duplex Resuspension Buffer - 2 ml
Format:
Lyophilized
Storage:
-20 °C
Catalog No. ABIN3354885
$440.00
1 kit
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
gRNA + gRNA
Application:
Genome Editing with Engineered Nucleases
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
Gene ID:
5244 (Human, ABCB4)
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Vector type:
Lentiviral Vector
Vector backbone:
pCLIP-dual-SFFV-ZsGreen
Resistance Gene:
Ampicillin, Zeocin
Selection Marker:
Puromycin
Promoter:
SFFV Promoter, U6 Promoter
Fusion Tag:
ZsGreen
Expression:
Transient, Stable

Viral particles:
ABIN5057578

Components:
- Two vectors containing two gRNAs in each vector
- Negative control
- Available as bacterial glycerol stocks or viral particles
- Cas9 expression vectors can be purchased separately
Format:
Glycerol Stock
Storage:
-80 °C
Catalog No. ABIN5038633
$503.00
1 set
Plus shipping costs $45.00
Will be delivered in 16 Business Days

Type:
ORF
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_000443
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Cloning Vector
Vector backbone:
pORF
Resistance Gene:
Spectinomycin
Expression:
Transient

Sequencing Primer:
  • M13 FP: 5'-CCCAGTCACGACGTTGTAAAACG-3'
    M13 RP: 5'-CAGGAAACAGCTATGAC-3'
Format:
Liquid
Buffer:
10  mM Tris-HCI, 1  mM EDTA,  pH 8.0
Storage:
-20 °C
Catalog No. ABIN5737626
$511.00
1 μg
Plus shipping costs $45.00
Delivery in 3 to 4 Business Days

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_000443
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
His tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4421618
$520.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_000443
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
HA tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4486704
$520.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-N-D-C-HA
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag,HA tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4497987
$520.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Protein Expression
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Mammalian Expression Vector
Vector backbone:
pPM-N-D-C-His
Resistance Gene:
Kanamycin
Selection Marker:
Neomycin
Promoter:
CMV Promoter
Fusion Tag:
DYKDDDDK Tag,His tag
Expression:
Stable, Transient

Sequencing Primer:
  • CMV sequencing primer: 5` CGC AAA TGG GCG GTA GGC GTG 3`
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4559196
$520.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_000443
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-N-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient

Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4630175
$520.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_000443
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-MBP
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-MBP
Expression:
Transient

Sequencing Primer:
  • MBP Forward primer: 5'-CGCAGATGTCCGCTTTCTGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4696782
$520.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_000443
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-C-His
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His tag
Expression:
Transient

Sequencing Primer:
  • T7 promoter primer: 5'-TAATACGACTCACTATAGGG-3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4778396
$520.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days

Type:
cDNA
Application:
Cloning
Gene:
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4)
NCBI Accession:
NM_000443
Species:
Human
Synonyms:
ABCB4, abcb4, Abcb4, LOC100861170, LOC101122517
Insert length:
540 bp
Vector type:
Bacterial Expression Vector
Vector backbone:
pPB-His-GST
Resistance Gene:
Kanamycin
Promoter:
T7 Promoter
Fusion Tag:
His-GST
Expression:
Transient

Sequencing Primer:
  • GST Forward primer: 5'-CACGTTTGGTGGTGGCGAC3'
  • T7 terminator primer: 5'-GCTAGTTATTGCTCAGCGG-3'
Format:
Liquid
Buffer:
10 mM Tris-HCI, 1 mM EDTA, pH 8.0
Storage:
-20 °C
Catalog No. ABIN4825911
$520.00
500 ng
Plus shipping costs $45.00
Delivery in 11 to 21 Business Days
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  • 1

Synonyms and alternative names related to ABCB4

  • ATP binding cassette subfamily B member 4 (ABCB4)
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (abcb4)
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (Abcb4)
  • ATP binding cassette subfamily B member 4 (Abcb4)
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (ABCB4)
  • beta-defensin 1-like (LOC100861170)
  • RUN domain-containing protein 3B (LOC101122517)
  • ABC21
  • ABCB4
  • ABCB4a
  • DEFB1
  • GBD1
  • ICP3
  • mdr-2
  • Mdr2
  • MDR2
  • MDR2/3
  • MDR3
  • PFIC-3
  • PGP3
  • Pgy-2
  • Pgy2
  • PGY3
  • Pgy3
  • RUNDC3B
  • zgc:172149

Gene-IDs for different species

GENE IDSPECIES
5244 Homo sapiens
100136865 Danio rerio
100144586 Sus scrofa
748364 Pan troglodytes
18670 Mus musculus
24891 Rattus norvegicus
482284 Canis lupus familiaris
756756 Strongylocentrotus purpuratus
100398854 Callithrix jacchus
100455534 Pongo abelii
100462975 Monodelphis domestica
100475375 Ailuropoda melanoleuca
100354947 Oryctolagus cuniculus
100861170 Capra hircus
100682535 Cricetulus griseus
100147513 Equus caballus
101122517 Ovis aries musimon
100336913 Bos taurus

Protein level used designations for ABCB4

  • ATP-binding cassette sub-family B member 4
  • P glycoprotein 3/multiple drug resistance 3
  • P-glycoprotein 3
  • P-glycoprotein-3/multiple drug resistance-3
  • multidrug resistance protein 3
  • multiple drug resistance 3
  • ABC efflux transporter 4
  • abcb1b
  • multidrug resistance 3
  • ATP-binding cassette, subfamily B, member 4
  • P glycoprotein 2
  • multidrug resistance protein 2
  • ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2
  • ATP-binding cassette sub-family B (MDR/TAP) member 4 (P-glycoprotein 3/ multidrug resistance 2)
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4 (P-glycoprotein 3/ multidrug resistance 2)
  • P-glycoprotein 2
  • P-glycoprotein 3/ multidrug resistance 2
  • ATP-binding cassette, sub-family B (MDR/TAP), member 4
  • multidrug resistance protein 3-like
  • ATP-binding cassette transporter protein
  • Beta-defensin 1
  • Defensin, beta 1
  • p-glycoprotein isoform III
  • LOW QUALITY PROTEIN: phosphatidylcholine translocator ABCB4
  • RUN domain containing 3B
  • RUN domain-containing protein 3B
  • phosphatidylcholine translocator ABCB4
  • P glycoprotein 3/ multiple drug resistance 3
Other products related to ABCB4 such as antibodies, ELISA kits and high-purity proteins are available on our partner website antibodies-online.com